α,N,O-TMS
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α,N,O-Trimethylserotonin (α,N,O-TMS), also known as 5-methoxy-α,N-dimethyltryptamine (5-MeO-α,N-DMT), is a psychedelic drug of the tryptamine and α-alkyltryptamine families. It is taken orally.
Use and effects
In his book TiHKAL (Tryptamines I Have Known and Loved), Shulgin lists the dose as 10 to 20mg orally and the duration as 6 to 8hours. The drug is significantly less potent than its non-N-methylated parent compound 5-MeO-AMT (5-methoxy-α-methyltryptamine), which has a dose range of 2.5 to 4.5mg and a duration of 12 to 18hours.
Interactions
Chemistry
Synthesis
The chemical synthesis of α,N,O-TMS has been described.
Analogues
Analogues of α,N,O-TMS (N-methyl-5-MeO-AMT) include α-methyltryptamine (AMT), α,N-DMT (N-methyl-AMT), α,N,N-TMT (N,N-dimethyl-AMT), α-methylserotonin (AMS; 5-HO-AMT), 5-MeO-AMT (α,O-DMS), and α,N,N,O-TeMS (N,N-dimethyl-5-MeO-AMT), among others.