16BO133 is a SARS-like coronavirus (SL-COV) which was found in the greater horseshoe bat in South Korea. It was published in 2019 and its genome was completely sequenced. The sequenced Korean SARSr-CoV strain belongs to the severe acute respiratory syndrome coronavirus 1, and its genome sequence similarity is 82.8%.

Discovery

The 16BO133 virus was discovered in the oral cavity of the greater horseshoe bat in 2016. The genome of this virus strain is 29075 nt. Among SARSr-CoVs, 16BO133 is the closest to the JTMC15 virus, which was published in 2016 and discovered in Jilin, China, with a genome nucleic acid sequence similarity of 98.3%. Compared with other SARSr-CoVs, these two viruses have the ORF8 strain due to a frameshift mutation at the end of ORF7b. The similarity of the genome nucleic acid sequence of 16BO133 virus and SARS-CoV is 82.8%.

Although other SARSr-CoV strains have been found in Korea in the past (B15-21 virus, etc.), none of them have been sequenced. The 16BO133 virus is the first Korean SARSr-CoV strain to be completely sequenced.

Phylogenetic

A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:

SARS‑CoV‑1 related coronavirus16BO133, 86.3% to SARS-CoV-1, Rhinolophus ferrumequinum, North Jeolla, South Korea JTMC15, 86.4% to SARS-CoV-1, Rhinolophus ferrumequinum, Tonghua, Jilin Bat SARS CoV Rf1, 87.8% to SARS-CoV-1, Rhinolophus ferrumequinum, Yichang, Hubei BtCoV HKU3, 87.9% to SARS-CoV-1, Rhinolophus sinicus, Hong Kong and Guangdong LYRa11, 90.9% to SARS-CoV-1, Rhinolophus affinis, Baoshan, Yunnan Bat SARS-CoV/Rp3, 92.6% to SARS-CoV-1, Rhinolophus pearsoni, Nanning, Guangxi Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
16BO133, 86.3% to SARS-CoV-1, Rhinolophus ferrumequinum, North Jeolla, South Korea JTMC15, 86.4% to SARS-CoV-1, Rhinolophus ferrumequinum, Tonghua, Jilin Bat SARS CoV Rf1, 87.8% to SARS-CoV-1, Rhinolophus ferrumequinum, Yichang, Hubei BtCoV HKU3, 87.9% to SARS-CoV-1, Rhinolophus sinicus, Hong Kong and Guangdong LYRa11, 90.9% to SARS-CoV-1, Rhinolophus affinis, Baoshan, Yunnan Bat SARS-CoV/Rp3, 92.6% to SARS-CoV-1, Rhinolophus pearsoni, Nanning, Guangxi Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
16BO133, 86.3% to SARS-CoV-1, Rhinolophus ferrumequinum, North Jeolla, South Korea JTMC15, 86.4% to SARS-CoV-1, Rhinolophus ferrumequinum, Tonghua, Jilin Bat SARS CoV Rf1, 87.8% to SARS-CoV-1, Rhinolophus ferrumequinum, Yichang, Hubei
16BO133, 86.3% to SARS-CoV-1, Rhinolophus ferrumequinum, North Jeolla, South Korea JTMC15, 86.4% to SARS-CoV-1, Rhinolophus ferrumequinum, Tonghua, Jilin
16BO133, 86.3% to SARS-CoV-1, Rhinolophus ferrumequinum, North Jeolla, South Korea
JTMC15, 86.4% to SARS-CoV-1, Rhinolophus ferrumequinum, Tonghua, Jilin
Bat SARS CoV Rf1, 87.8% to SARS-CoV-1, Rhinolophus ferrumequinum, Yichang, Hubei
BtCoV HKU3, 87.9% to SARS-CoV-1, Rhinolophus sinicus, Hong Kong and Guangdong
BtCoV HKU3, 87.9% to SARS-CoV-1, Rhinolophus sinicus, Hong Kong and Guangdong
LYRa11, 90.9% to SARS-CoV-1, Rhinolophus affinis, Baoshan, Yunnan Bat SARS-CoV/Rp3, 92.6% to SARS-CoV-1, Rhinolophus pearsoni, Nanning, Guangxi Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
LYRa11, 90.9% to SARS-CoV-1, Rhinolophus affinis, Baoshan, Yunnan
Bat SARS-CoV/Rp3, 92.6% to SARS-CoV-1, Rhinolophus pearsoni, Nanning, Guangxi Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
Bat SARS-CoV/Rp3, 92.6% to SARS-CoV-1, Rhinolophus pearsoni, Nanning, Guangxi
Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan
Bat SL-CoV YNLF_31C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan
Bat SL-CoV YNLF_34C, 93.5% to SARS-CoV-1, Rhinolophus ferrumequinum, Lufeng, Yunnan
SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan
SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan
SHC014-CoV, 95.4% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan
WIV1, 95.6% to SARS-CoV-1, Rhinolophus sinicus, Kunming, Yunnan
WIV16, 96.0% to SARS-CoV-1, Rhinolophus sinicus Kunming, Yunnan
Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China SARS-CoV-1
Civet SARS-CoV, 99.8% to SARS-CoV-1, Paguma larvata, market in Guangdong, China
SARS-CoV-1
SARS-CoV-2, 79% to SARS-CoV-1

See also

  • Data related to 16BO133 at Wikispecies