The year 1878 in science and technology involved many significant events, listed below.

Astronomy

Biology

Chemistry

Conservation

Exploration

August – Cleopatra's Needle (horizontal) being raised in London.

Geology

Mathematics

Medicine

  • Cesare Lombroso publishes L'uomo delinquente, setting out his theory of criminal atavism.
  • Ádám Politzer publishes Lehrbuch der Ohrenheilkunde, a major otology textbook.
  • Dentists Act in the United Kingdom limits the title of "dentist" and "dental surgeon" to qualified and registered practitioners.

Meteorology

  • February 11 – The first weekly weather report is published in the United Kingdom.

Paleontology

Physics

Technology

Institutions

Awards

Births

Deaths