The 1925–26 Challenge Cup was the 26th staging of rugby league's oldest knockout competition, the Challenge Cup.
First round
| Date | Team one | Score one | Team two | Score two |
|---|
| 13 Feb | Barnsley Utd | 0 | Hull Kingston Rovers | 28 |
| 13 Feb | Barrow | 44 | Barrow Cambridge St | 0 |
| 13 Feb | Bradford Northern | 2 | Keighley | 2 |
| 13 Feb | Bramley | 0 | Rochdale Hornets | 11 |
| 13 Feb | Castleford | 12 | St Helens Recs | 18 |
| 13 Feb | Featherstone Rovers | 7 | Broughton Rangers | 8 |
| 13 Feb | Halifax | 16 | Dewsbury | 0 |
| 13 Feb | Hensingham | 0 | Huddersfield | 33 |
| 13 Feb | Hull FC | 27 | Pemberton Rovers | 3 |
| 13 Feb | Hunslet | 7 | Warrington | 11 |
| 13 Feb | Leigh | 6 | Oldham | 18 |
| 13 Feb | Salford | 2 | Leeds | 3 |
| 13 Feb | Swinton | 19 | Batley | 9 |
| 13 Feb | Widnes | 7 | St Helens | 10 |
| 13 Feb | Wigan Highfield | 7 | Wakefield Trinity | 2 |
| 13 Feb | Wigan | 45 | York | 10 |
| 17 Feb | Keighley | 5 | Bradford Northern | 5 |
| 22 Feb | Bradford Northern | 9 | Keighley | 4 |
Second round
| Date | Team one | Score one | Team two | Score two |
|---|
| 27 Feb | Barrow | 0 | Halifax | 3 |
| 27 Feb | Bradford Northern | 3 | Hull Kingston Rovers | 6 |
| 27 Feb | Leeds | 17 | Wigan | 10 |
| 27 Feb | Oldham | 12 | Rochdale Hornets | 3 |
| 27 Feb | St Helens | 7 | Hull FC | 10 |
| 27 Feb | Swinton | 8 | Broughton Rangers | 8 |
| 27 Feb | Warrington | 17 | St Helens Recs | 12 |
| 27 Feb | Wigan Highfield | 5 | Huddersfield | 3 |
| 03 Mar | Broughton Rangers | 3 | Swinton | 20 |
Quarterfinals
| Date | Team one | Score one | Team two | Score two |
|---|
| 13 Mar | Hull FC | 15 | Warrington | 2 |
| 13 Mar | Oldham | 8 | Halifax | 5 |
| 13 Mar | Swinton | 24 | Hull Kingston Rovers | 3 |
| 13 Mar | Wigan Highfield | 11 | Leeds | 2 |
Semifinals
| Date | Team one | Score one | Team two | Score two |
|---|
| 27 Mar | Oldham | 15 | Wigan Highfield | 6 |
| 27 Mar | Swinton | 13 | Hull FC | 2 |
Final
Swinton beat Oldham 9-3 in the final played at Rochdale before a crowd of 27,000.
This was Swinton's second appearance in the final and their second Cup final win. Their previous victory was in 1900.
| Swinton | 9 – 3 | Oldham |
|---|
| Tries: Blewer Goals: Morris (3) | | Tries: Corsi |
| Athletic Grounds, Rochdale Attendance: 27,800 Referee: A. Brown (Wakefield) |
| |
|---|
| FB 1 Jack Pearson RW 2 Frank Evans RC 3 Wilf Sulway LC 4 Jack Evans LW 5 William Rees SO 6 Chris Brockbank SH 7 Bryn Evans PR 8 Miller Strong HK 9 Henry Blewer PR 10 Herbert Morris SR 11 Tom Halliwell SR 12 Harry Entwistle LF 13 Fred Beswick Coach: | FB 1 Ernest Knapman RW 2 Albert Brough RC 3 Sid Rix LC 4 Alf Higgs LW 5 Joe Corsi SO 6 Reg Jones SH 7 George Hesketh PR 8 Rothwell Marlor HK 9 Bert Lister PR 10 Jack Read SR 11 Percy Carter SR 12 Bob Sloman LF 13 Ambrose Baker Coach: |
| FB | 1 | Jack Pearson |
| RW | 2 | Frank Evans |
| RC | 3 | Wilf Sulway |
| LC | 4 | Jack Evans |
| LW | 5 | William Rees |
| SO | 6 | Chris Brockbank |
| SH | 7 | Bryn Evans |
| PR | 8 | Miller Strong |
| HK | 9 | Henry Blewer |
| PR | 10 | Herbert Morris |
| SR | 11 | Tom Halliwell |
| SR | 12 | Harry Entwistle |
| LF | 13 | Fred Beswick |
| Coach: |
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| |
| FB | 1 | Ernest Knapman |
| RW | 2 | Albert Brough |
| RC | 3 | Sid Rix |
| LC | 4 | Alf Higgs |
| LW | 5 | Joe Corsi |
| SO | 6 | Reg Jones |
| SH | 7 | George Hesketh |
| PR | 8 | Rothwell Marlor |
| HK | 9 | Bert Lister |
| PR | 10 | Jack Read |
| SR | 11 | Percy Carter |
| SR | 12 | Bob Sloman |
| LF | 13 | Ambrose Baker |
| Coach: |
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