| 1 | 0.5– | Dallas Cowboys | Selection forfeited during the 1989 supplemental draft. |
| 1 | 1 | Indianapolis Colts | Jeff George | QB | Illinois | from Atlanta |
| 1 | 2 | New York Jets | Blair Thomas | RB | Penn State | |
| 1 | 2.5– | Phoenix Cardinals | Selection forfeited during the 1989 supplemental draft. |
| 1 | 3 | Seattle Seahawks | Cortez Kennedy‡† | DT | Miami (FL) | from New England |
| 1 | 4 | Tampa Bay Buccaneers | Keith McCants | LB | Alabama | |
| 1 | 5 | San Diego Chargers | Junior Seau‡† | LB | USC | |
| 1 | 6 | Chicago Bears | Mark Carrier† | S | USC | |
| 1 | 7 | Detroit Lions | Andre Ware | QB | Houston | 1989 Heisman Trophy winner |
| 1 | 8 | New England Patriots | Chris Singleton | LB | Arizona | from Seattle |
| 1 | 9 | Miami Dolphins | Richmond Webb† | T | Texas A&M | |
| 1 | 10 | New England Patriots | Ray Agnew | DE | NC State | from Indianapolis via Seattle |
| 1 | 11 | Los Angeles Raiders | Anthony Smith | DE | Arizona | |
| 1 | 12 | Cincinnati Bengals | James Francis | LB | Baylor | |
| 1 | 13 | Kansas City Chiefs | Percy Snow | LB | Michigan State | |
| 1 | 14 | New Orleans Saints | Renaldo Turnbull† | LB | West Virginia | |
| 1 | 15 | Houston Oilers | Lamar Lathon† | LB | Houston | |
| 1 | 16 | Buffalo Bills | James Williams | CB | Fresno State | |
| 1 | 17 | Dallas Cowboys | Emmitt Smith‡† | RB | Florida | from Pittsburgh |
| 1 | 18 | Green Bay Packers | Tony Bennett | LB | Ole Miss | from Cleveland |
| 1 | 19 | Green Bay Packers | Darrell Thompson | RB | Minnesota | |
| 1 | 20 | Atlanta Falcons | Steve Broussard | RB | Washington State | from Washington |
| 1 | 21 | Pittsburgh Steelers | Eric Green | TE | Liberty | from Minnesota via Dallas |
| 1 | 22 | Philadelphia Eagles | Ben Smith | CB | Georgia | |
| 1 | 23 | Los Angeles Rams | Bern Brostek | C | Washington | |
| 1 | 24 | New York Giants | Rodney Hampton† | RB | Georgia | |
| 1 | 24.5– | Denver Broncos | Selection forfeited during the 1989 supplemental draft. |
| 1 | 25 | San Francisco 49ers | Dexter Carter | RB | Florida State | |
| 2 | 26 | Dallas Cowboys | Alexander Wright | WR | Auburn | |
| 2 | 27 | Atlanta Falcons | Darion Conner | LB | Jackson State | |
| 2 | 28 | New York Jets | Reggie Rembert | WR | West Virginia | |
| 2 | 29 | Seattle Seahawks | Terry Wooden | LB | Syracuse | from New England |
| 2 | 30 | Tampa Bay Buccaneers | Reggie Cobb | RB | Tennessee | |
| 2 | 31 | Phoenix Cardinals | Anthony Thompson | RB | Indiana | |
| 2 | 32 | Chicago Bears | Fred Washington | DT | TCU | |
| 2 | 33 | Chicago Bears | Ron Cox | LB | Fresno State | from San Diego |
| 2 | 34 | Seattle Seahawks | Robert Blackmon | S | Baylor | |
| 2 | 35 | Detroit Lions | Dan Owens | DE | USC | |
| 2 | 36 | Indianapolis Colts | Anthony Johnson | RB | Notre Dame | |
| 2 | 37 | Los Angeles Raiders | Aaron Wallace | LB | Texas A&M | |
| 2 | 38 | Cincinnati Bengals | Harold Green† | RB | South Carolina | |
| 2 | 39 | Miami Dolphins | Keith Sims† | G | Iowa State | |
| 2 | 40 | Kansas City Chiefs | Tim Grunhard† | C | Notre Dame | |
| 2 | 41 | Houston Oilers | Jeff Alm | DT | Notre Dame | |
| 2 | 42 | Buffalo Bills | Carwell Gardner | RB | Louisville | |
| 2 | 43 | Pittsburgh Steelers | Kenny Davidson | DE | LSU | |
| 2 | 44 | New Orleans Saints | Vince Buck | CB | Central State | |
| 2 | 45 | Cleveland Browns | Leroy Hoard† | RB | Michigan | |
| 2 | 46 | Washington Redskins | Andre Collins | LB | Penn State | |
| 2 | 47 | San Francisco 49ers | Dennis Brown | DE | Washington | from Minnesota via Dallas |
| 2 | 48 | Green Bay Packers | LeRoy Butler‡† | S | Florida State | |
| 2 | 49 | Los Angeles Rams | Pat Terrell | S | Notre Dame | |
| 2 | 50 | Philadelphia Eagles | Mike Bellamy | WR | Illinois | |
| 2 | 51 | New York Giants | Mike Fox | DE | West Virginia | |
| 2 | 52 | Denver Broncos | Alton Montgomery | S | Houston | |
| 2 | 53 | San Francisco 49ers | Eric Davis† | CB | Jacksonville State | |
| 3 | 54 | Minnesota Vikings | Mike Jones | TE | Texas A&M | from Dallas |
| 3 | 55 | Atlanta Falcons | Oliver Barnett | DE | Kentucky | |
| 3 | 56 | New York Jets | Tony Stargell | CB | Tennessee State | |
| 3 | 57 | San Diego Chargers | Jeff Mills | LB | Nebraska | from Tampa Bay |
| 3 | 58 | Phoenix Cardinals | Ricky Proehl | WR | Wake Forest | |
| 3 | 59 | New England Patriots | Tommy Hodson | QB | LSU | |
| 3 | 60 | San Diego Chargers | Leo Goeas | G | Hawaii | |
| 3 | 61 | Chicago Bears | Tim Ryan | DT | USC | |
| 3 | 62 | Detroit Lions | Marc Spindler | DE | Pittsburgh | |
| 3 | 63 | Chicago Bears | Peter Tom Willis | QB | Florida State | from LA Raiders |
| 3 | 64 | Dallas Cowboys | Jimmie Jones | DT | Miami (FL) | from Seattle via New England |
| 3 | 65 | Cincinnati Bengals | Bernard Clark | LB | Miami (FL) | |
| 3 | 66 | Miami Dolphins | Alfred Oglesby | DT | Houston | |
| 3 | 67 | San Diego Chargers | Walter Wilson | WR | East Carolina | from Indianapolis |
| 3 | 68 | San Francisco 49ers | Ron Lewis | WR | Florida State | from Kansas City via Dallas |
| 3 | 69 | Buffalo Bills | Glenn Parker | G | Arizona | |
| 3 | 70 | Pittsburgh Steelers | Neil O'Donnell† | QB | Maryland | |
| 3 | 71 | New Orleans Saints | Joel Smeenge | DE | Western Michigan | |
| 3 | 72 | Houston Oilers | Willis Peguese | DE | Miami (FL) | |
| 3 | 73 | Cleveland Browns | Anthony Pleasant | DE | Tennessee State | |
| 3 | 74 | Minnesota Vikings | Marion Hobby | DE | Tennessee | |
| 3 | 75 | Green Bay Packers | Bobby Houston | LB | NC State | |
| 3 | 76 | Washington Redskins | Mohammed Elewonibi | T | BYU | |
| 3 | 77 | Philadelphia Eagles | Fred Barnett† | WR | Arkansas State | |
| 3 | 78 | Los Angeles Rams | Latin Berry | CB | Oregon | |
| 3 | 79 | New York Giants | Greg Mark | LB | Miami (FL) | |
| 3 | 80 | New England Patriots | Greg McMurtry | WR | Michigan | from Denver via Dallas |
| 3 | 81 | Pittsburgh Steelers | Craig Veasey | DT | Houston | from San Francisco via Dallas |
| 4 | 82 | Denver Broncos | Jeroy Robinson | LB | Texas A&M | from Dallas |
| 4 | 83 | Indianapolis Colts | Stacey Simmons | WR | Florida | from Atlanta |
| 4 | 84 | New York Jets | Troy Taylor | QB | California | |
| 4 | 85 | Phoenix Cardinals | Davis, TravisTravisDavis | DT | Michigan State | |
| 4 | 86 | Washington Redskins | Cary Conklin | QB | Washington | from New England |
| 4 | 87 | Tampa Bay Buccaneers | Jess Anderson | TE | Mississippi State | |
| 4 | 88 | Chicago Bears | Tony Moss | WR | LSU | |
| 4 | 89 | Seattle Seahawks | Chris Warren† | RB | Ferrum | |
| 4 | 90 | Detroit Lions | Hinckley, RobRobHinckley | LB | Stanford | |
| 4 | 91 | Cincinnati Bengals | Mike Brennan | G | Notre Dame | |
| 4 | 92 | San Francisco 49ers | Dean Caliguire | C | Pittsburgh | from San Diego via LA Raiders |
| 4 | 93 | Miami Dolphins | Scott Mitchell | QB | Utah | |
| 4 | 94 | Indianapolis Colts | Bill Schultz | G | USC | |
| 4 | 95 | Los Angeles Raiders | Torin Dorn | CB | North Carolina | |
| 4 | 96 | Kansas City Chiefs | Fred Jones | WR | Grambling State | |
| 4 | 97 | Pittsburgh Steelers | Chris Calloway | WR | Michigan | |
| 4 | 98 | New Orleans Saints | DeMond Winston | LB | Vanderbilt | |
| 4 | 99 | Houston Oilers | Eric Still | G | Tennessee | |
| 4 | 100 | Buffalo Bills | Eddie Fuller | RB | LSU | |
| 4 | 101 | Cleveland Browns | Harlon Barnett | S | Michigan State | |
| 4 | 102 | Green Bay Packers | Jackie Harris† | TE | Northeast Louisiana | |
| 4 | 103 | Indianapolis Colts | Alan Grant | CB | Stanford | from Washington |
| 4 | 104 | Minnesota Vikings | Alonzo Hampton | CB | Pittsburgh | |
| 4 | 105 | Detroit Lions | Chris Oldham | S | Oregon | from LA Rams |
| 4 | 106 | Indianapolis Colts | Rick Cunningham | G | Texas A&M | from Philadelphia |
| 4 | 107 | New York Giants | David Whitmore | S | Stephen F. Austin | |
| 4 | 108 | Tampa Bay Buccaneers | Tony Mayberry† | C | Wake Forest | from Denver |
| 4 | 109 | Washington Redskins | Labbe, RicoRicoLabbe | CB | Boston College | from San Francisco via LA Raiders |
| 5 | 110 | New England Patriots | Junior Robinson | CB | East Carolina | from Dallas via Washington |
| 5 | 111 | Denver Broncos | Jeff Davidson | G | Ohio State | from Atlanta via Washington and New England |
| 5 | 112 | New York Jets | Tony Savage | DT | Washington State | |
| 5 | 113 | New England Patriots | Jon Melander | G | Minnesota | |
| 5 | 114 | Tampa Bay Buccaneers | Ian Beckles | G | Indiana | |
| 5 | 115 | Phoenix Cardinals | Larry Centers† | FB | Stephen F. Austin | |
| 5 | 116 | Minnesota Vikings | Reggie Thornton | WR | Bowling Green | from San Diego via Dallas |
| 5 | 117 | Chicago Bears | Pat Chaffey | RB | Oregon State | |
| 5 | 118 | Detroit Lions | Jeff Campbell | WR | Colorado | |
| 5 | 119 | Seattle Seahawks | Eric Hayes | DT | Florida State | |
| 5 | 120 | New England Patriots | Gary, JamesJamesGary | RB | Texas Tech | from Miami via Dallas |
| 5 | 121 | Atlanta Falcons | Reggie Redding | T | Cal State Fullerton | from Indianapolis |
| 5 | 122 | Cincinnati Bengals | Lynn James | WR | Arizona State | |
| 5 | 123 | Los Angeles Raiders | Stan Smagala | DB | Notre Dame | |
| 5 | 124 | Kansas City Chiefs | Derrick Graham | T | Appalachian State | |
| 5 | 125 | New Orleans Saints | Charles Arbuckle | TE | UCLA | |
| 5 | 126 | Houston Oilers | Richard Newbill | LB | Miami (FL) | |
| 5 | 127 | Kansas City Chiefs | Hackemack, KenKenHackemack | T | Texas | from Buffalo |
| 5 | 128 | Pittsburgh Steelers | Barry Foster† | RB | Arkansas | |
| 5 | 129 | Cleveland Browns | Rob Burnett† | DE | Syracuse | |
| 5 | 130 | Washington Redskins | Brian Mitchell† | RB | Northeast Louisiana | |
| 5 | 131 | Minnesota Vikings | Cedric Smith | RB | Florida | |
| 5 | 132 | Green Bay Packers | Charles Wilson | WR | Memphis | |
| 5 | 133 | Philadelphia Eagles | Calvin Williams | WR | Purdue | |
| 5 | 134 | New York Jets | McWright, RobertRobertMcWright | DB | TCU | from LA Rams |
| 5 | 135 | New York Giants | Craig Kupp | QB | Pacific Lutheran | |
| 5 | 136 | Denver Broncos | Le-Lo Lang | CB | Washington | |
| 5 | 137 | Miami Dolphins | Leroy Holt | FB | USC | from San Francisco via LA Raiders and Washington |
| 6 | 138 | San Diego Chargers | John Friesz | QB | Idaho | from Dallas |
| 6 | 139 | Atlanta Falcons | Mike Pringle | RB | Cal State Fullerton | |
| 6 | 140 | New York Jets | Terance Mathis† | WR | New Mexico | |
| 6 | 141 | Tampa Bay Buccaneers | Derrick Douglas | RB | Louisiana Tech | |
| 6 | 142 | Phoenix Cardinals | Shavers, TyroneTyroneShavers | WR | Lamar | |
| 6 | 143 | San Diego Chargers | Frank Cornish | C | UCLA | from New England via Dallas |
| 6 | 144 | Chicago Bears | John Mangum | CB | Alabama | |
| 6 | 145 | San Diego Chargers | David Pool | CB | Carson–Newman | |
| 6 | 146 | Seattle Seahawks | Ned Bolcar | LB | Notre Dame | |
| 6 | 147 | Detroit Lions | Maurice Henry | LB | Kansas State | |
| 6 | 148 | Indianapolis Colts | Tony Walker | LB | Southeast Missouri State | |
| 6 | 149 | Los Angeles Raiders | Marcus Wilson | RB | Virginia | |
| 6 | 150 | Cincinnati Bengals | Don Odegard | CB | UNLV | |
| 6 | 151 | Miami Dolphins | Sean Vanhorse | CB | Howard | |
| 6 | 152 | Kansas City Chiefs | Tom Sims | DT | Pittsburgh | |
| 6 | 153 | Houston Oilers | Tony Jones | WR | Texas | |
| 6 | 154 | Buffalo Bills | John Nies | P | Arizona | |
| 6 | 155 | Pittsburgh Steelers | Heard, RonaldRonaldHeard | WR | Bowling Green | |
| 6 | 156 | New Orleans Saints | Mike Buck | QB | Maine | |
| 6 | 157 | Cleveland Browns | Randy Hilliard | CB | Northwestern State | |
| 6 | 158 | New Orleans Saints | James Williams | LB | Mississippi State | from Minnesota via Dallas and LA Raiders |
| 6 | 159 | Green Bay Packers | Bryce Paup† | LB | Northern Iowa | |
| 6 | 160 | Washington Redskins | Kent Wells | DT | Nebraska | |
| 6 | 161 | Los Angeles Rams | Tim Stallworth | WR | Washington State | |
| 6 | 162 | Philadelphia Eagles | Thompson, KevinKevinThompson | DB | Oklahoma | |
| 6 | 163 | San Diego Chargers | Derrick Walker | TE | Michigan | from NY Giants via Dallas |
| 6 | 164 | Denver Broncos | Ronnie Haliburton | LB | LSU | |
| 6 | 165 | San Francisco 49ers | Frank Pollack | T | Northern Arizona | |
| 7 | 166 | Buffalo Bills | Griffith, BrentBrentGriffith | G | Minnesota Duluth | from Dallas via New England |
| 7 | 167 | New York Jets | Dwayne White | G | Alcorn State | from Atlanta |
| 7 | 168 | New York Jets | Proctor, BasilBasilProctor | LB | West Virginia | |
| 7 | 169 | Phoenix Cardinals | Johnny Johnson† | RB | San Jose State | |
| 7 | 170 | Buffalo Bills | Collins, BrentBrentCollins | LB | Carson–Newman | from New England |
| 7 | 171 | Tampa Bay Buccaneers | Donnie Gardner | DE | Kentucky | |
| 7 | 172 | San Diego Chargers | Jeff Novak | G | Southwest Texas State | |
| 7 | 173 | Los Angeles Raiders | Garry Lewis | CB | Alcorn State | from Chicago |
| 7 | 174 | Detroit Lions | Tracy Hayworth | LB | Tennessee | |
| 7 | 175 | Seattle Seahawks | Bob Kula | T | Michigan State | |
| 7 | 176 | Chicago Bears | Anderson, BillBillAnderson | C | Iowa | from LA Raiders |
| 7 | 177 | Cincinnati Bengals | Craig Ogletree | LB | Auburn | |
| 7 | 178 | Cleveland Browns | Scott Galbraith | TE | USC | from Miami |
| 7 | 179 | Indianapolis Colts | Singletary, JamesJamesSingletary | LB | East Carolina | |
| 7 | 180 | Kansas City Chiefs | Dave Szott† | G | Penn State | |
| 7 | 181 | Buffalo Bills | DeRiggi, FredFredDeRiggi | DT | Syracuse | |
| 7 | 182 | Pittsburgh Steelers | Dan Grayson | LB | Washington State | |
| 7 | 183 | New Orleans Saints | Hough, ScottScottHough | G | Maine | |
| 7 | 184 | Houston Oilers | Murray, AndyAndyMurray | RB | Kentucky | |
| 7 | 185 | San Diego Chargers | Joe Staysniak | G | Ohio State | from Cleveland |
| 7 | 186 | Green Bay Packers | Lester Archambeau | DE | Stanford | |
| 7 | 187 | San Diego Chargers | Nate Lewis | WR | Oregon Tech | from Washington |
| 7 | 188 | Minnesota Vikings | Levelis, JohnJohnLevelis | LB | C.W. Post | |
| 7 | 189 | Philadelphia Eagles | Strouf, TerryTerryStrouf | T | Wisconsin–La Crosse | |
| 7 | 190 | Los Angeles Rams | Elmore, KentKentElmore | P | Tennessee | |
| 7 | 191 | New York Giants | Emanuel, AaronAaronEmanuel | RB | USC | |
| 7 | 192 | Denver Broncos | Shannon Sharpe‡† | TE | Savannah State | |
| 7 | 193 | San Diego Chargers | Collins, KeithKeithCollins | DB | Appalachian State | from San Francisco |
| 8 | 194 | Detroit Lions | Willie Green | WR | Mississippi | from Dallas |
| 8 | 195 | Atlanta Falcons | Tory Epps | DT | Memphis State | |
| 8 | 196 | New York Jets | Roger Duffy | C | Penn State | |
| 8 | 197 | Los Angeles Raiders | Arthur Jimerson | DE | Norfolk State | from New England via Dallas |
| 8 | 198 | Los Angeles Rams | Savage, RayRaySavage | LB | Virginia | from Tampa Bay |
| 8 | 199 | Phoenix Cardinals | Mickey Washington | CB | Texas A&M | |
| 8 | 200 | Chicago Bears | James Rouse | RB | Arkansas | |
| 8 | 201 | San Diego Chargers | Flannigan, J. J.J. J.Flannigan | RB | Colorado | |
| 8 | 202 | Seattle Seahawks | Bill Hitchcock | G | Purdue | |
| 8 | 203 | Detroit Lions | Roman Fortin | C | San Diego State | |
| 8 | 204 | Cincinnati Bengals | Doug Wellsandt | TE | Washington State | |
| 8 | 205 | Miami Dolphins | Woods, ThomasThomasWoods | WR | Tennessee | |
| 8 | 206 | Indianapolis Colts | Ken Clark | RB | Nebraska | |
| 8 | 207 | New Orleans Saints | Gerry Gdowski | QB | Nebraska | from LA Raiders |
| 8 | 208 | Buffalo Bills | Marvcus Patton | LB | UCLA | from Kansas City |
| 8 | 209 | Pittsburgh Steelers | Karl Dunbar | DE | Louisiana State | |
| 8 | 210 | New Orleans Saints | Carr, DerrickDerrickCarr | DE | Bowling Green | |
| 8 | 211 | Houston Oilers | Tucker, BrettBrettTucker | DB | NIU | |
| 8 | 211.5– | Buffalo Bills | Selection forfeited during the 1989 supplemental draft. |
| 8 | 212 | Cleveland Browns | Jock Jones | LB | Virginia Tech | |
| 8 | 213 | Indianapolis Colts | Wilson, HarveyHarveyWilson | DB | Southern U. | from Washington |
| 8 | 214 | Minnesota Vikings | Schlichting, CraigCraigSchlichting | DE | Wyoming | |
| 8 | 215 | Green Bay Packers | Roger Brown | CB | Virginia Tech | |
| 8 | 216 | Los Angeles Rams | Elbert Crawford | G | Arkansas | |
| 8 | 217 | Philadelphia Eagles | Dykes, CurtCurtDykes | T | Oregon | |
| 8 | 218 | New York Giants | Voorhees, BarryBarryVoorhees | T | Cal State Northridge | |
| 8 | 219 | Denver Broncos | Brad Leggett | C | USC | |
| 8 | 220 | San Francisco 49ers | Pickens, DwightDwightPickens | WR | Fresno State | |
| 9 | 221 | Dallas Cowboys | Kenneth Gant | DB | Albany State | |
| 9 | 222 | Atlanta Falcons | Jordan, DarrellDarrellJordan | LB | Northern Arizona | |
| 9 | 223 | New York Jets | Dale Dawkins | WR | Miami (FL) | |
| 9 | 224 | Tampa Bay Buccaneers | Cook, TerryTerryCook | DE | Fresno State | |
| 9 | 225 | Phoenix Cardinals | David Bavaro | LB | Syracuse | |
| 9 | 226 | New England Patriots | Shawn Bouwens | G | Nebraska Wesleyan | |
| 9 | 227 | San Diego Chargers | Goetz, ChrisChrisGoetz | G | Pittsburgh | |
| 9 | 228 | Chicago Bears | Johnny Bailey† | RB | Texas A&M–Kingsville | |
| 9 | 229 | Detroit Lions | Jack Linn | T | West Virginia | |
| 9 | 230 | Los Angeles Raiders | Perry, LeonLeonPerry | RB | Oklahoma | from Seattle via Dallas |
| 9 | 231 | Miami Dolphins | Ross, PhilPhilRoss | TE | Oregon State | |
| 9 | 232 | Indianapolis Colts | Darvell Huffman | WR | Boston University | |
| 9 | 233 | New Orleans Saints | Graves, BroderickBroderickGraves | RB | Winston-Salem | from LA Raiders |
| 9 | 234 | Cincinnati Bengals | Mitchell Price | CB | Tulane | |
| 9 | 235 | Kansas City Chiefs | Owens, MichaelMichaelOwens | RB | Syracuse | |
| 9 | 236 | New Orleans Saints | Brockman, LonnieLonnieBrockman | LB | West Virginia | |
| 9 | 237 | Houston Oilers | Pat Coleman | WR | Ole Miss | |
| 9 | 238 | Buffalo Bills | Clarkston Hines | WR | Duke | |
| 9 | 239 | Pittsburgh Steelers | Gary Jones | S | Texas A&M | |
| 9 | 240 | Cleveland Browns | Rowell, EugeneEugeneRowell | WR | Southern Miss | |
| 9 | 241 | Minnesota Vikings | Terry Allen† | RB | Clemson | |
| 9 | 242 | Green Bay Packers | Kirk Baumgartner | QB | Wisconsin–Stevens Point | |
| 9 | 243 | Washington Redskins | Moxley, TimTimMoxley | G | Ohio State | |
| 9 | 244 | Philadelphia Eagles | Cecil Gray | T | North Carolina | |
| 9 | 245 | Los Angeles Rams | Tony Lomack | WR | Florida | |
| 9 | 246 | New York Giants | James, ClintClintJames | DE | LSU | |
| 9 | 247 | Denver Broncos | Todd Ellis | QB | South Carolina | |
| 9 | 248 | San Francisco 49ers | Odell Haggins | DT | Florida State | |
| 10 | 249 | Minnesota Vikings | Pat Newman | WR | Utah State | from Dallas |
| 10 | 250 | Atlanta Falcons | Salum, DonnieDonnieSalum | LB | Arizona | |
| 10 | 251 | New York Jets | Brad Quast | LB | Iowa | |
| 10 | 252 | Phoenix Cardinals | Elle, DaveDaveElle | TE | South Dakota | |
| 10 | 253 | New England Patriots | Landry, AnthonyAnthonyLandry | RB | Stephen F. Austin | |
| 10 | 254 | Tampa Bay Buccaneers | Mike Busch | TE | Iowa State | |
| 10 | 255 | Chicago Bears | Price, TerryTerryPrice | DE | Texas A&M | |
| 10 | 256 | San Diego Chargers | Berry, KennyKennyBerry | DB | Miami (FL) | |
| 10 | 257 | Seattle Seahawks | Morris, RobertRobertMorris | DE | Valdosta State | |
| 10 | 258 | Detroit Lions | Miller, BillBillMiller | WR | Illinois State | |
| 10 | 259 | Denver Broncos | Jim Szymanski | DE | Michigan State | from Indianapolis via Dallas and LA Raiders |
| 10 | 260 | New Orleans Saints | Cooper, GaryGaryCooper | WR | Clemson | from LA Raiders |
| 10 | 261 | Cincinnati Bengals | Crigler, EricEricCrigler | T | Murray State | |
| 10 | 262 | Washington Redskins | Francisco, D'JuanD'JuanFrancisco | DB | Notre Dame | from Miami |
| 10 | 263 | Kansas City Chiefs | Hudson, CraigCraigHudson | TE | Wisconsin | |
| 10 | 264 | Houston Oilers | Dee Thomas | DB | Nicholls State | |
| 10 | 265 | Buffalo Bills | Mike Lodish | DT | UCLA | |
| 10 | 266 | Pittsburgh Steelers | Eddie Miles | LB | Minnesota | |
| 10 | 267 | New Orleans Saints | Ernest Spears | DB | USC | |
| 10 | 268 | Cleveland Browns | Wallace, MichaelMichaelWallace | DB | Jackson State | |
| 10 | 269 | Green Bay Packers | Martin, JeromeJeromeMartin | DB | Western Kentucky | |
| 10 | 270 | Washington Redskins | Thomas Rayam | G | Alabama | |
| 10 | 271 | Minnesota Vikings | Donald Smith | DB | Liberty | |
| 10 | 272 | Los Angeles Rams | Bates, SteveSteveBates | DE | James Madison | |
| 10 | 273 | Philadelphia Eagles | Adams, OrlandoOrlandoAdams | DT | Jacksonville State | |
| 10 | 274 | New York Giants | Moore, OtisOtisMoore | DT | Clemson | |
| 10 | 275 | Denver Broncos | Thompson, AnthonyAnthonyThompson | LB | East Carolina | |
| 10 | 276 | San Francisco 49ers | Martin Harrison | DE | Washington | |
| 11 | 277 | Dallas Cowboys | Dave Harper | LB | Humboldt State | |
| 11 | 278 | Atlanta Falcons | Ellison, ChrisChrisEllison | DB | Houston | |
| 11 | 279 | New York Jets | Kelson, DerrickDerrickKelson | DB | Purdue | |
| 11 | 280 | New England Patriots | Sean Smith | DE | Georgia Tech | |
| 11 | 281 | Tampa Bay Buccaneers | Terry Anthony | WR | Florida State | |
| 11 | 282 | Phoenix Cardinals | Norman, DempseyDempseyNorman | WR | St. Francis (IL) | |
| 11 | 283 | San Diego Chargers | Tommie Stowers | TE | Missouri | |
| 11 | 284 | Chicago Bears | White, BrentBrentWhite | DE | Michigan | |
| 11 | 285 | Detroit Lions | Warnsley, ReginaldReginaldWarnsley | RB | Southern Miss | |
| 11 | 286 | Seattle Seahawks | Reed, DarylDarylReed | DB | Oregon | |
| 11 | 287 | New Orleans Saints | Webbie Burnett | DT | Western Kentucky | from LA Raiders |
| 11 | 288 | Cincinnati Bengals | O'Connor, TimTimO'Connor | T | Virginia | |
| 11 | 289 | San Francisco 49ers | Anthony Shelton | S | Tennessee State | from Miami |
| 11 | 290 | Indianapolis Colts | Smith, CarnelCarnelSmith | DE | Pittsburgh | |
| 11 | 291 | Kansas City Chiefs | Thompson, ErnestErnestThompson | RB | Georgia Southern | |
| 11 | 292 | Buffalo Bills | Al Edwards | WR | Northwestern State | |
| 11 | 293 | Pittsburgh Steelers | Justin Strzelczyk | G | Maine | |
| 11 | 294 | Philadelphia Eagles | John Hudson | G | Auburn | from New Orleans |
| 11 | 295 | Houston Oilers | Joey Banes | T | Houston | |
| 11 | 296 | Cleveland Browns | Clemente Gordon | QB | Grambling State | |
| 11 | 297 | Washington Redskins | Leverenz, JonJonLeverenz | LB | Minnesota | |
| 11 | 298 | Chicago Bears | Matusz, RomanRomanMatusz | T | Pittsburgh | from Minnesota via LA Raiders |
| 11 | 299 | Green Bay Packers | Jackson, HarryHarryJackson | RB | St. Cloud State | |
| 11 | 300 | Philadelphia Eagles | Watson, TyroneTyroneWatson | WR | Tennessee State | |
| 11 | 301 | Los Angeles Rams | Bill Goldberg | DE | Georgia | |
| 11 | 302 | New York Giants | Downing, TimTimDowning | DE | Washington State | |
| 11 | 303 | Los Angeles Raiders | Lewis, RonRonLewis | WR | Jackson State | from Denver |
| 11 | 304 | Los Angeles Raiders | Jones, MyronMyronJones | RB | Fresno State | from San Francisco via Dallas |
| 12 | 304.5– | Dallas Cowboys | Selection forfeited during the 1989 supplemental draft. |
| 12 | 305 | Atlanta Falcons | Shawn McCarthy | P | Purdue | |
| 12 | 306 | New York Jets | Darrell Davis | DE | TCU | |
| 12 | 307 | Tampa Bay Buccaneers | Todd Hammel | QB | Stephen F. Austin | |
| 12 | 308 | Phoenix Cardinals | Riley, DonnieDonnieRiley | RB | Central Michigan | |
| 12 | 309 | New England Patriots | Donelson, VentsonVentsonDonelson | DB | Michigan State | |
| 12 | 310 | Chicago Bears | Cooney, AnthonyAnthonyCooney | DB | Arkansas | |
| 12 | 311 | Indianapolis Colts | Benhart, GeneGeneBenhart | QB | Western Illinois | from San Diego |
| 12 | 312 | Seattle Seahawks | Gromos, JohnJohnGromos | QB | Vanderbilt | |
| 12 | 313 | Detroit Lions | Robert Claiborne | WR | San Diego State | |
| 12 | 314 | Cincinnati Bengals | Riley, AndreAndreRiley | WR | Washington | |
| 12 | 315 | Miami Dolphins | Bobby Harden | S | Miami (FL) | |
| 12 | 316 | Indianapolis Colts | Brown, DeanDeanBrown | G | Notre Dame | |
| 12 | 317 | Los Angeles Raiders | Major Harris | QB | West Virginia | |
| 12 | 318 | Kansas City Chiefs | Jeffery, TonyTonyJeffery | WR | San Jose State | |
| 12 | 319 | Pittsburgh Steelers | Richard Bell | RB | Nebraska | |
| 12 | 320 | New Orleans Saints | Chris Port | G | Duke | |
| 12 | 321 | Houston Oilers | Reggie Slack | QB | Auburn | |
| 12 | 322 | New England Patriots | Rose, BlaineBlaineRose | G | Maryland | from Buffalo |
| 12 | 323 | Cleveland Browns | Simien, KerryKerrySimien | WR | Texas A&M–Kingsville | |
| 12 | 324 | Minnesota Vikings | Ron Goetz | LB | Minnesota | |
| 12 | 325 | Green Bay Packers | Maggio, KirkKirkMaggio | P | UCLA | |
| 12 | 326 | San Diego Chargers | Searcy, ElliottElliottSearcy | WR | Southern | from Washington |
| 12 | 327 | Philadelphia Eagles | Judd Garrett | RB | Princeton | |
| 12 | 328 | Los Angeles Rams | David Lang | RB | Northern Arizona | |
| 12 | 329 | New York Giants | Matt Stover† | K | Louisiana Tech | |
| 12 | 330 | Phoenix Cardinals | McMichel, KenKenMcMichel | DB | Oklahoma | from Denver |
| 12 | 331 | Los Angeles Rams | Davis, DemetriusDemetriusDavis | TE | Nevada | from San Francisco |