The knockout phase of the 2010 CAF Champions League will begin on 1 October 2010 and conclude by 14 November 2010. The knockout phase involves the four teams who finished in the top two in each of their groups in the group stage. Each tie is played over two legs, with each team playing one leg at home. The team that has the higher aggregate score over the two legs progresses to the next round. In the event that aggregate scores finish level, the team that scored more goals away from home over the two legs progresses. If away goals are also equal, the tie is decided by a penalty shoot-out – with no extra time being held.

Qualified teams

GroupWinnersRunners-up
ATunisia Espérance STDemocratic Republic of the Congo TP Mazembe
BAlgeria JS KabylieEgypt Al-Ahly

Semifinals

Al-Ahly Egypt2 – 1Tunisia Espérance ST
Fadl 38' Fathy 68'Darragi 72'
Espérance ST Tunisia1 – 0Egypt Al-Ahly
Eneramo 1'

Aggregate 2 – 2. Espérance ST advanced on the away goals rule to the 2010 CAF Champions League Final.


TP Mazembe Democratic Republic of the Congo3 – 1Algeria JS Kabylie
Kaluyituka 6', 89' Kasongo 85'Yaâlaoui 69'
JS Kabylie Algeria0 – 0Democratic Republic of the Congo TP Mazembe

TP Mazembe won 3 – 1 on aggregate and advanced to the 2010 CAF Champions League Final.

Final

TP Mazembe Democratic Republic of the Congo5 – 0Tunisia Espérance ST
Kasongo 18', 74' Kaluyituka 45+2' (pen.) Singuluma 56', 59'
Espérance ST Tunisia1 – 1Democratic Republic of the Congo TP Mazembe
Afful 23'Kanda A Mukok 69'

TP Mazembe won 6 – 1 on aggregate.