The 2021 Major League Baseball draft took place on July 11–13, 2021. In conjunction with the 2021 Major League Baseball All-Star Game, the draft was held in Denver. The draft assigned amateur baseball players to MLB teams. The draft order was set based on the reverse order of the 2020 MLB season standings. In addition, compensation picks were distributed for players who did not sign from the 2020 MLB draft and for teams who lost qualifying free agents. On March 26, 2020, MLB and the MLBPA reached a deal that included the option to halve the draft to 20 rounds due to the COVID-19 pandemic. MLB ultimately opted to shorten the draft to 20 rounds. In total, 612 college and high school players were drafted.

The Pittsburgh Pirates, who had the worst record of the 2020 season, selected Henry Davis with the first overall pick in the draft. As punishment for their role in the sign stealing scandal, the Houston Astros forfeited both their first- and second-round picks in the draft.

On April 2, 2021, MLB announced that the 2021 MLB All-Star Game, along with the draft, was being relocated from Atlanta in protest of the Georgia State Legislature's passage of the Election Integrity Act of 2021; three days later, Denver was announced as the new host city.

Chase Silseth made his MLB debut for the Los Angeles Angels on May 13, 2022, making him the first player from the 2021 draft to make his major league debut.

Draft selections

The deadline for teams to sign drafted players was August 1, 2021.

Key
All-Star
*Player did not sign

First round

PickPlayerTeamPositionSchool
1Henry DavisPittsburgh PiratesCatcherLouisville
2Jack LeiterTexas RangersPitcherVanderbilt
3Jackson JobeDetroit TigersPitcherHeritage Hall School (OK)
4Marcelo MayerBoston Red SoxShortstopEastlake High School (CA)
5Colton CowserBaltimore OriolesOutfielderSam Houston State
6Jordan LawlarArizona DiamondbacksShortstopJesuit Dallas (TX)
7Frank MozzicatoKansas City RoyalsPitcherEast Catholic High School (CT)
8Benny MontgomeryColorado RockiesOutfielderRed Land High School (PA)
9Sam BachmanLos Angeles AngelsPitcherMiami (OH)
10Kumar Rocker*New York MetsPitcherVanderbilt
11Brady HouseWashington NationalsShortstopWinder-Barrow High School (GA)
12Harry FordSeattle MarinersCatcherNorth Cobb High School (GA)
13Andrew PainterPhiladelphia PhilliesPitcherCalvary Christian Academy (FL)
14Will BednarSan Francisco GiantsPitcherMississippi State
15Sal FrelickMilwaukee BrewersOutfielderBoston College
16Kahlil WatsonMiami MarlinsShortstopWake Forest High School (NC)
17Matt McLainCincinnati RedsShortstopUCLA
18Michael McGreevySt. Louis CardinalsPitcherUC Santa Barbara
19Gunnar HoglundToronto Blue JaysPitcherOle Miss
20Trey SweeneyNew York YankeesShortstopEastern Illinois University (IL)
21Jordan WicksChicago CubsPitcherKansas State
22Colson MontgomeryChicago White SoxShortstopSouthridge High School (IN)
23Gavin WilliamsCleveland IndiansPitcherEast Carolina
24Ryan CusickAtlanta BravesPitcherWake Forest
25Max MuncyOakland AthleticsShortstopThousand Oaks High School (CA)
26Chase PettyMinnesota TwinsPitcherMainland Regional High School (NJ)
27Jackson MerrillSan Diego PadresShortstopSeverna Park High School (MD)
28Carson WilliamsTampa Bay RaysShortstopTorrey Pines High School (CA)
29Maddux BrunsLos Angeles DodgersPitcherUMS-Wright Preparatory School (AL)

Compensatory round

PickPlayerTeamPositionSchool
30Jay AllenCincinnati RedsOutfielderJohn Carroll Catholic High School (FL)

Competitive balance round A

PickPlayerTeamPositionSchool
31Joe MackMiami MarlinsCatcherWilliamsville East High School (NY)
32Ty MaddenDetroit TigersPitcherTexas
33Tyler BlackMilwaukee BrewersSecond basemanWright State
34Cooper KinneyTampa Bay RaysSecond basemanBaylor School (TN)
35Matheu NelsonCincinnati RedsCatcherFlorida State
36Noah MillerMinnesota TwinsShortstopOzaukee High School (WI)

Second round

PickPlayerTeamPositionSchool
37Anthony SolometoPittsburgh PiratesPitcherBishop Eustace Preparatory School (NJ)
38Aaron ZavalaTexas RangersOutfielderOregon
39Izaac PachecoDetroit TigersThird basemanFriendswood High School (TX)
40Jud Fabian*Boston Red SoxOutfielderFlorida
41Connor NorbyBaltimore OriolesSecond basemanEast Carolina
42Ryan BlissArizona DiamondbacksShortstopAuburn
43Ben KudrnaKansas City RoyalsPitcherBlue Valley Southwest High School (KS)
44Jaden HillColorado RockiesPitcherLSU
45Ky BushLos Angeles AngelsPitcherSaint Mary's
46Calvin ZieglerNew York MetsPitcherTNXL Academy (FL)
47Daylen LileWashington NationalsOutfielderTrinity High School (KY)
48Edwin ArroyoSeattle MarinersShortstopArecibo Baseball Academy (PR)
49Ethan WilsonPhiladelphia PhilliesOutfielderSouth Alabama
50Matt MikulskiSan Francisco GiantsPitcherFordham
51Russell SmithMilwaukee BrewersPitcherTCU
52Cody MorissetteMiami MarlinsShortstopBoston College
53Andrew AbbottCincinnati RedsPitcherVirginia
54Joshua BáezSt. Louis CardinalsOutfielderDexter Southfield School (MA)
55Brendan BeckNew York YankeesPitcherStanford
56James TriantosChicago CubsThird basemanJames Madison High School (VA)
57Wes KathChicago White SoxThird basemanDesert Mountain High School (AZ)
58Doug NikhazyCleveland IndiansPitcherOle Miss
59Spencer SchwellenbachAtlanta BravesPitcherNebraska
60Zack GelofOakland AthleticsThird basemanVirginia
61Steve HajjarMinnesota TwinsPitcherMichigan
62James WoodSan Diego PadresOutfielderIMG Academy (FL)
63Kyle ManzardoTampa Bay RaysFirst basemanWashington State

Competitive balance round B

PickPlayerTeamPositionSchool
64Lonnie WhitePittsburgh PiratesOutfielderMalvern Preparatory School (PA)
65Reed TrimbleBaltimore OriolesOutfielderSouthern Miss
66Peyton WilsonKansas City RoyalsSecond basemanAlabama
67Adrian Del CastilloArizona DiamondbacksCatcherMiami (FL)
68Joe RockColorado RockiesPitcherOhio
69Tommy MaceCleveland IndiansPitcherFlorida
70Ryan HolgateSt. Louis CardinalsOutfielderArizona
71Robert GasserSan Diego PadresPitcherHouston

Other notable selections

RoundPickPlayerTeamPositionSchool
372Bubba ChandlerPittsburgh PiratesPitcherNorth Oconee High School (GA)
373Cameron CauleyTexas RangersShortstopBarbers Hill High School (TX)
374Dylan SmithDetroit TigersPitcherAlabama
376John RhodesBaltimore OriolesOutfielderKentucky
377Jacob SteinmetzArizona DiamondbacksPitcherELEV8 Baseball Academy (FL)
378Carter JensenKansas City RoyalsCatcherPark Hill High School (MO)
380Landon MarceauxLos Angeles AngelsPitcherLSU
384Jordan ViarsPhiladelphia PhilliesOutfielderReedy High School (TX)
385Mason BlackSan Francisco GiantsPitcherLehigh
386Alex BinelasMilwaukee BrewersThird basemanLouisville
391Ricky TiedemannToronto Blue JaysPitcherGolden West College
392Brock SelvidgeNew York YankeesPitcherHamilton High School (AZ)
394Sean BurkeChicago White SoxPitcherMaryland
395Jake FoxCleveland IndiansSecond baseman / OutfielderLakeland Christian School (FL)
396Dylan DoddAtlanta BravesPitcherSoutheast Missouri State
397Mason MillerOakland AthleticsPitcherGardner-Webb
398Cade PovichMinnesota TwinsPitcherNebraska
399Kevin KoppsSan Diego PadresPitcherArkansas
4104Tyler MattisonDetroit TigersPitcherBryant
4109Hunter GoodmanColorado RockiesCatcherMemphis
4110Luke MurphyLos Angeles AngelsPitcherVanderbilt
4113Bryce MillerSeattle MarinersPitcherTexas A&M
4116Logan HendersonMilwaukee BrewersPitcherMcLennan Community College
4118Tanner AllenMiami MarlinsOutfielderMississippi State
4121Chad DallasToronto Blue JaysPitcherTennessee
4122Cooper BowmanNew York YankeesSecond basemanLouisville
4123Christian FranklinChicago CubsOutfielderArkansas
4126Cal ConleyAtlanta BravesShortstopTexas Tech
4127Denzel ClarkeOakland AthleticsOutfielderCal State Northridge
4128Christian Encarnacion-StrandMinnesota TwinsThird basemanOklahoma State
4129Jackson WolfSan Diego PadresPitcherWest Virginia
4131Nick NastriniLos Angeles DodgersPitcherUCLA
4132Chayce McDermottHouston AstrosPitcherBall State
5136Nathan HickeyBoston Red SoxCatcherFlorida
5140Evan JusticeColorado RockiesPitcherNC State
5141Brett KerryLos Angeles AngelsPitcherSouth Carolina
5142Christian ScottNew York MetsPitcherFlorida
5145Griff McGarryPhiladelphia PhilliesPitcherVirginia
5148Quincy HamiltonHouston AstrosOutfielderWright State
5151Gordon GraceffoSt. Louis CardinalsPitcherVillanova
5154Liam SpenceChicago CubsShortstopTennessee
5156Tanner BibeeCleveland IndiansPitcherCal State Fullerton
5157Luke WaddellAtlanta BravesShortstopGeorgia Tech
5160Max FergusonSan Diego PadresSecond basemanTennessee
5162Ben CaspariusLos Angeles DodgersPitcherUConn
6164Chase LeeTexas RangersPitcherAlabama
6170Braxton FulfordColorado RockiesCatcherTexas Tech
6174Bryan WooSeattle MarinersPitcherCal Poly
6178Spencer ArrighettiHouston AstrosPitcherLouisiana
6182Hayden JuengerToronto Blue JaysPitcherMissouri State
6183Richard FittsNew York YankeesPitcherAuburn
6187Justyn-Henry MalloyAtlanta BravesFirst basemanGeorgia Tech
6189Travis AdamsMinnesota TwinsPitcherSacramento State
6190Ryan BergertSan Diego PadresPitcherWest Virginia
6191Mason MontgomeryTampa Bay RaysPitcherTexas Tech
6192Emmet SheehanLos Angeles DodgersPitcherBoston College
7195Brant HurterDetroit TigersPitcherGeorgia Tech
7199Noah CameronKansas City RoyalsPitcherCentral Arkansas
7203Jacob YoungWashington NationalsOutfielderUniversity of Florida
7207Tristan PetersMilwaukee BrewersOutfielderSouthern Illinois
7208Joey LoperfidoHouston AstrosOutfielderDuke
7213Robby AhlstromNew York YankeesPitcherOregon
7216Jack LeftwichCleveland IndiansPitcherFlorida
7217AJ Smith-ShawverAtlanta BravesPitcherColleyville Heritage High School (TX)
7218Brett HarrisOakland AthleticsThird basemanGonzaga
7219Jake RuckerMinnesota TwinsThird basemanTennessee
8226Hunter DobbinsBoston Red SoxPitcherTexas Tech
8227Creed WillemsBaltimore OriolesCatcherAledo High School (TX)
8230Robby MartinColorado RockiesOutfielderFlorida State
8232Mike VasilNew York MetsPitcherVirginia
8238Colton GordonHouston AstrosPitcherUCF
8239Patrick MonteverdeMiami MarlinsPitcherTexas Tech
8243Will WarrenNew York YankeesPitcherSoutheastern Louisiana
8245Fraser EllardChicago White SoxPitcherLiberty
9254Liam HicksTexas RangersCatcherArkansas State
9255Garrett BurhennDetroit TigersPitcherOhio State
9261Braden OlthoffLos Angeles AngelsPitcherTulane
9273Chandler ChamplainNew York YankeesPitcherUSC
9276Will DionCleveland IndiansPitcherMcNeese State
10287Billy CookBaltimore OriolesFirst baseman / OutfielderPepperdine
10293Darren BakerWashington NationalsSecond basemanCalifornia
10295Logan CernyPhiladelphia PhilliesOutfielderTroy
10303Ben CowlesNew York YankeesShortstopMaryland
10306Franco AlemánCleveland IndiansPitcherFlorida
10308Jack WinklerOakland AthleticsInfielderSan Francisco
11316Niko KavadasBoston Red SoxFirst basemanNotre Dame
11321Chase SilsethLos Angeles AngelsPitcherArizona
11327Roc Riggio*Milwaukee BrewersSecond basemanThousand Oaks (CA)
11339Brandon Birdsell*Minnesota TwinsPitcherTexas Tech
11340River RyanSan Diego PadresPitcherUNC Pembroke
11342Justin WrobleskiLos Angeles DodgersPitcherOklahoma State
12347Justin ArmbruesterBaltimore OriolesPitcherNew Mexico
12355T. J. RumfieldPhiladelphia PhilliesFirst basemanVirginia Tech
12356Landen RouppSan Francisco GiantsPitcherUNC Wilmington
12358Rhett KoubaHouston AstrosPitcherDallas Baptist
12360Julian AguiarCincinnati RedsPitcherCypress College
12363Ben RiceNew York YankeesCatcherDartmouth
12367Andrew HoffmannAtlanta BravesPitcherIllinois
12372Ronan KoppLos Angeles DodgersPitcherSouth Mountain Community College
13392Matt SvansonToronto Blue JaysPitcherLehigh
13393Zach MessingerNew York YankeesPitcherVirginia
13399David FestaMinnesota TwinsPitcherSeton Hall
13401Bob SeymourTampa Bay RaysFirst basemanWake Forest
14411Eric TorresLos Angeles AngelsPitcherKansas State
14412Nathan LavenderNew York MetsPitcherIllinois
14421Andre GranilloSt. Louis CardinalsPitcherUC Riverside
14427Caleb DurbinAtlanta BravesShortstopWashington University
14429Pierson OhlMinnesota TwinsPitcherGrand Canyon
14432Jordan LeasureLos Angeles DodgersPitcherTampa
15437Keagan GilliesBaltimore OriolesPitcherTulane
15453Danny WatsonNew York YankeesPitcherVCU
16490Alek JacobSan Diego PadresPitcherGonzaga
16492Mike Sirota*Los Angeles DodgersShortstopThe Frederick Gunn School (CT)
17496Luis GuerreroBoston Red SoxPitcherChipola College
17499Luca TreshKansas City RoyalsCatcherNC State
17501Mason ErlaLos Angeles AngelsPitcherMichigan State
18538Will WagnerHouston AstrosSecond basemanLiberty
18550Gage Jump*San Diego PadresPitcherJSerra Catholic High School (CA)
19555Justice BigbieDetroit TigersFirst basemanWestern Carolina
19557Alex PhamBaltimore OriolesPitcherSan Francisco
19565Seth Halvorsen*Philadelphia PhilliesPitcherMissouri
19573Dominic Keegan*New York YankeesUtilityVanderbilt
20596Vance Honeycutt*San Francisco GiantsShortstopSalisbury High School (NC)
20597Samuel MendezMilwaukee BrewersPitcherCisco College
20602Luke Holman*Toronto Blue JaysPitcherWilson High School (PA)
20610Chase Burns*San Diego PadresPitcherBeech Senior High School (TN)

Notes

Compensation picks