AMELY

Identifiers

Aliases, AMGL, AMGY, amelogenin, Y-linked, amelogenin Y-linked

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Y chromosome (human)

Band Yp11.2 Start 6,865,918 bp

End6,911,752 bp

Gene location ( Mouse )

Chr.X chromosome (mouse)

Band X F5|X 78.95 cM Start 167,959,110 bp

End167,970,196 bp

RNA expression patternHumanMouse (ortholog)testicle gonad sural nerve placenta Ventricular system of neuraxis ventricular zone thyroid gland left lobe of thyroid gland hepatobiliary system pancreasmolar embryo mandibular molars nucleus pulposus sexually immature organism temporal muscle ascending aorta aortic valve olfactory epithelium tibiofemoral jointn/a

RNA expression pattern

HumanMouse (ortholog)testicle gonad sural nerve placenta Ventricular system of neuraxis ventricular zone thyroid gland left lobe of thyroid gland hepatobiliary system pancreasmolar embryo mandibular molars nucleus pulposus sexually immature organism temporal muscle ascending aorta aortic valve olfactory epithelium tibiofemoral joint

Human Mouse (ortholog)

testicle gonad sural nerve placenta Ventricular system of neuraxis ventricular zone thyroid gland left lobe of thyroid gland hepatobiliary system pancreasmolar embryo mandibular molars nucleus pulposus sexually immature organism temporal muscle ascending aorta aortic valve olfactory epithelium tibiofemoral joint

testicle gonad sural nerve placenta Ventricular system of neuraxis ventricular zone thyroid gland left lobe of thyroid gland hepatobiliary system pancreas

molar embryo mandibular molars nucleus pulposus sexually immature organism temporal muscle ascending aorta aortic valve olfactory epithelium tibiofemoral joint

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY gene. AMELY is located on the Y chromosome and encodes a form of amelogenin. Amelogenin is an extracellular matrix protein involved in biomineralization during tooth enamel development.

Clinical significance

Mutations in the related AMELX gene on the X chromosome cause X-linked amelogenesis imperfecta.

External links

Human genome location and gene details page in the UCSC Genome Browser.

AMELY

Clinical significance

External links

Further reading