Autocrine motility factor receptor, isoform 2 is a protein that in humans is encoded by the AMFR gene.

Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.

Interactions

AMFR has been shown to interact with Valosin-containing protein.

External links

Further reading