Synergin gamma

SYNRG

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Identifiers

Aliases, AP1GBP1, SYNG, synergin, gamma, synergin gamma

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 17 (human)

Band 17q12 Start 37,514,807 bp

End37,609,472 bp

Gene location ( Mouse )

Chr.Chromosome 11 (mouse)

Band 11|11 C Start 83,855,254 bp

End83,935,404 bp

RNA expression patternHumanMouse (ortholog)bone marrow cell tonsil epithelium of colon sural nerve lymph node islet of Langerhans granulocyte appendix corpus callosum ganglionic eminencezygote spermatocyte spermatid muscle of thigh dentate gyrus of hippocampal formation granule cell secondary oocyte granulocyte neural layer of retina ventricular zone superior frontal gyrusn/a

RNA expression pattern

HumanMouse (ortholog)bone marrow cell tonsil epithelium of colon sural nerve lymph node islet of Langerhans granulocyte appendix corpus callosum ganglionic eminencezygote spermatocyte spermatid muscle of thigh dentate gyrus of hippocampal formation granule cell secondary oocyte granulocyte neural layer of retina ventricular zone superior frontal gyrus

Human Mouse (ortholog)

bone marrow cell tonsil epithelium of colon sural nerve lymph node islet of Langerhans granulocyte appendix corpus callosum ganglionic eminencezygote spermatocyte spermatid muscle of thigh dentate gyrus of hippocampal formation granule cell secondary oocyte granulocyte neural layer of retina ventricular zone superior frontal gyrus

bone marrow cell tonsil epithelium of colon sural nerve lymph node islet of Langerhans granulocyte appendix corpus callosum ganglionic eminence

zygote spermatocyte spermatid muscle of thigh dentate gyrus of hippocampal formation granule cell secondary oocyte granulocyte neural layer of retina ventricular zone superior frontal gyrus

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Synergin gamma also known as AP1 subunit gamma-binding protein 1 (AP1GBP1) is a protein that in humans is encoded by the SYNRG gene.

Function

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Interactions

AP1GBP1 has been shown to interact with AP1G1 and SCAMP1.

Synergin gamma

Function

Interactions

Further reading