ARMCX6
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Armadillo repeat containing X-linked 6 is a protein that in humans is encoded by the ARMCX6 gene located on the X-chromosome.
It is one of six armadillo repeats containing X-linked proteins (ARMCX1, ARMCX2, ARMCX3, ARMCX4, ARMCX5, and ARMCX6 (this protein)).
The function of this protein is unknown at this time.
Protein sequence
Homology
ARMCX6 is conserved in many eukaryotic organisms.
Orthologs
| taxonomic name | common name | NCBI entry | Percentage of sequence similarity | Length (AAs) | comments |
|---|---|---|---|---|---|
| Homo sapiens | Human | 100% | 300 | armadillo repeat containing X-linked 6 | |
| Macaca mulatta | Rhesus monkey | 97.0% | 300 | PREDICTED: similar to amrmadillo repeat containing, X-linked 6 (H. sapiens)-like isoform 1 | |
| Equus caballus | Horse | 90.0% | 300 | PREDICTED: similar to armadillo repeat containing, X-linked 6 | |
| Danio rerio | zebrafish | 84.0% | 301 | Similar to RIKEN cDNA 0610039K22 | |
| Mus musculus | House Mouse | 97.7% | 393 | armadillo repeat containing, X-linked 6 (H. sapiens)-like | |
| Bos taurus | cow | 83.0% | 301 | armadillo repeat containing, X-linked 6 | |
| Mus musculus | Mouse | 82.0% | 301 | armadillo repeat containing, X-linked 6 | |
| Takifugu rubripes | Tetradontoidea | 66.0% | 818 | aryl hydrocarbon receptor 2C | |
| Caenorhabditis elegans | C. elegans | 50.0% | 332 | Serpentine Receptor, class H family member (srh-216) | |
| Saccharomyces cerevisiae | Yeast | 70.0% | 910 | Hul5p | |
| Gallus gallus | Chicken | 52.0% | 317 | PREDICTED: hypothetical protein | |
Secondary Structure
The secondary structure of ARMCX6 is predicted to be similar to cyanase. A comparison of the two sequences is shown below.
Expression
Microarray data show that ARMCX6 is highly expressed during earliest stages of spermatogenesis in mice.
External links
- Human genome location and gene details page in the UCSC Genome Browser.