ATPAF1

Identifiers

Aliases, ATP11, ATP11p, ATP synthase mitochondrial F1 complex assembly factor 1

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p33 Start 46,632,737 bp

End46,673,867 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 D1 Start 115,642,009 bp

End115,679,852 bp

RNA expression patternHumanMouse (ortholog)myocardium of left ventricle cardiac muscle tissue of right atrium vastus lateralis muscle right adrenal cortex right ventricle apex of heart right auricle of heart gastrocnemius muscle muscle of thigh caudate nucleusfacial motor nucleus muscle of thigh anterior horn of spinal cord right kidney medial geniculate nucleus substantia nigra spermatid superior frontal gyrus tail of embryo lateral geniculate nucleusn/a

RNA expression pattern

HumanMouse (ortholog)myocardium of left ventricle cardiac muscle tissue of right atrium vastus lateralis muscle right adrenal cortex right ventricle apex of heart right auricle of heart gastrocnemius muscle muscle of thigh caudate nucleusfacial motor nucleus muscle of thigh anterior horn of spinal cord right kidney medial geniculate nucleus substantia nigra spermatid superior frontal gyrus tail of embryo lateral geniculate nucleus

Human Mouse (ortholog)

myocardium of left ventricle cardiac muscle tissue of right atrium vastus lateralis muscle right adrenal cortex right ventricle apex of heart right auricle of heart gastrocnemius muscle muscle of thigh caudate nucleusfacial motor nucleus muscle of thigh anterior horn of spinal cord right kidney medial geniculate nucleus substantia nigra spermatid superior frontal gyrus tail of embryo lateral geniculate nucleus

facial motor nucleus muscle of thigh anterior horn of spinal cord right kidney medial geniculate nucleus substantia nigra spermatid superior frontal gyrus tail of embryo lateral geniculate nucleus

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

ATP synthase mitochondrial F1 complex assembly factor 1, also known as ATP11 homolog, is a protein that in humans is encoded by the ATPAF1 gene.

Function

This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified, but the biological validity of some of these variants has not been determined.

External links

Human genome location and gene details page in the UCSC Genome Browser.

ATPAF1

Function

External links

Further reading