Baculoviral IAP repeat-containing protein 2

Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.

Function

cIAP1 is a member of the Inhibitor of Apoptosis family that inhibit apoptosis by interfering with the activation of caspases.

Interactions

BIRC2 has been shown to interact with:

• CASP9,
• DIABLO,
• GSPT1,
• HSP90B1,
• HTRA2,
• RIPK1,
• RIPK2
• TNFSF14,
• TRAF1,
• TRAF2, and
• UBC.

Further reading

External links

• Human genome location and gene details page in the UCSC Genome Browser.