CCT3

Available structuresPDBOrtholog search:List of PDB id codes,

Available structures

PDBOrtholog search:

List of PDB id codes,

List of PDB id codes

Identifiers

Aliases, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, chaperonin containing TCP1 subunit 3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1q22 Start 156,308,968 bp

End156,367,873 bp

Gene location ( Mouse )

Chr.Chromosome 3 (mouse)

Band 3 F1|3 38.79 cM Start 88,204,423 bp

End88,229,074 bp

RNA expression pattern

HumanMouse (ortholog)gonad embryo islet of Langerhans ventricular zone ganglionic eminence right adrenal gland smooth muscle tissue right testis left testis right adrenal cortexprimitive streak otic placode Paneth cell maxillary prominence saccule mandibular prominence otic vesicle condyle somite spermatocyte

Human Mouse (ortholog)

gonad embryo islet of Langerhans ventricular zone ganglionic eminence right adrenal gland smooth muscle tissue right testis left testis right adrenal cortexprimitive streak otic placode Paneth cell maxillary prominence saccule mandibular prominence otic vesicle condyle somite spermatocyte

gonad embryo islet of Langerhans ventricular zone ganglionic eminence right adrenal gland smooth muscle tissue right testis left testis right adrenal cortex

primitive streak otic placode Paneth cell maxillary prominence saccule mandibular prominence otic vesicle condyle somite spermatocyte

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene.

Function

This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Interactions

CCT3 has been shown to interact with PPP4C.

External links

Human genome location and gene details page in the UCSC Genome Browser.

CCT3

Function

Interactions

External links

Further reading