CLDN19

Identifiers

Aliases, HOMG5, claudin 19

External IDsOMIM: ; MGI: ; GeneCards:

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p34.2 Start 42,733,093 bp

End42,740,254 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 D2.1 Start 119,112,611 bp

End119,119,635 bp

RNA expression patternHumanMouse (ortholog)trigeminal ganglion spinal ganglia retinal pigment epithelium renal medulla tibial nerve vena cava epithelium of nasopharynx body of tongue ventral tegmental area tracheasciatic nerve right kidney inner renal medulla outer renal medulla spinal ganglia lip human kidney lens embryo muscle of thighn/a

RNA expression pattern

HumanMouse (ortholog)trigeminal ganglion spinal ganglia retinal pigment epithelium renal medulla tibial nerve vena cava epithelium of nasopharynx body of tongue ventral tegmental area tracheasciatic nerve right kidney inner renal medulla outer renal medulla spinal ganglia lip human kidney lens embryo muscle of thigh

Human Mouse (ortholog)

trigeminal ganglion spinal ganglia retinal pigment epithelium renal medulla tibial nerve vena cava epithelium of nasopharynx body of tongue ventral tegmental area tracheasciatic nerve right kidney inner renal medulla outer renal medulla spinal ganglia lip human kidney lens embryo muscle of thigh

trigeminal ganglion spinal ganglia retinal pigment epithelium renal medulla tibial nerve vena cava epithelium of nasopharynx body of tongue ventral tegmental area trachea

sciatic nerve right kidney inner renal medulla outer renal medulla spinal ganglia lip human kidney lens embryo muscle of thigh

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsDatabasesNCBI: ; OMA:SpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

DatabasesNCBI: ; OMA:

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Claudin-19 is a protein that in humans is encoded by the CLDN19 gene. It belongs to the group of claudins. Claudin-19 has been implicated in magnesium transport.

Claudins, such as CLDN19, are transmembrane proteins found at tight junctions. Tight junctions form barriers that control the passage of ions and molecules across an epithelial sheet and the movement of proteins and lipids between apical and basolateral domains of epithelial cells (Lee et al., 2006).[supplied by OMIM]

External links

Humangenome location andgene details page in theUCSC Genome Browser.

CLDN19

External links

Further reading