COG2

Identifiers

Aliases, LDLC, component of oligomeric golgi complex 2, CDG2Q

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1q42.2 Start 230,642,481 bp

End230,693,982 bp

Gene location ( Mouse )

Chr.Chromosome 8 (mouse)

Band 8|8 E2 Start 125,247,506 bp

End125,278,747 bp

RNA expression pattern

HumanMouse (ortholog)rectum right hemisphere of cerebellum right adrenal cortex pancreatic ductal cell islet of Langerhans gonad left adrenal gland left adrenal cortex granulocyte tibialis anterior muscleyolk sac lens granulocyte spermatocyte right kidney neural layer of retina epithelium of stomach muscle of thigh proximal tubule spermatid

Human Mouse (ortholog)

rectum right hemisphere of cerebellum right adrenal cortex pancreatic ductal cell islet of Langerhans gonad left adrenal gland left adrenal cortex granulocyte tibialis anterior muscleyolk sac lens granulocyte spermatocyte right kidney neural layer of retina epithelium of stomach muscle of thigh proximal tubule spermatid

rectum right hemisphere of cerebellum right adrenal cortex pancreatic ductal cell islet of Langerhans gonad left adrenal gland left adrenal cortex granulocyte tibialis anterior muscle

yolk sac lens granulocyte spermatocyte right kidney neural layer of retina epithelium of stomach muscle of thigh proximal tubule spermatid

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Conserved oligomeric Golgi complex subunit 2 is a protein that in humans is encoded by the COG2 gene.

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002).

Interactions

COG2 has been shown to interact with COG4 and COG3.

External links

Human genome location and gene details page in the UCSC Genome Browser.

COG2

Interactions

External links

Further reading