Complement component 6

Available structuresPDBHuman UniProt search:List of PDB id codes, ,

Available structures

PDBHuman UniProt search:

List of PDB id codes, ,

List of PDB id codes

, ,

Identifiers

Aliases, complement C6

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 5 (human)

Band 5p13.1 Start 41,142,116 bp

End41,261,438 bp

Gene location ( Mouse )

Chr.Chromosome 15 (mouse)

Band 15 A1|15 1.97 cM Start 4,756,657 bp

End4,844,449 bp

RNA expression patternHumanMouse (ortholog)right lobe of liver right ventricle cardiac muscle tissue of right atrium right uterine tube myocardium of left ventricle right auricle of heart body of pancreas bronchial epithelial cell pancreatic ductal cell apex of heartleft lobe of liver mesenteric lymph nodes right lung lobe left lung left lung lobe white adipose tissue spleen mucosa of small intestine subcutaneous adipose tissue embryon/a

RNA expression pattern

HumanMouse (ortholog)right lobe of liver right ventricle cardiac muscle tissue of right atrium right uterine tube myocardium of left ventricle right auricle of heart body of pancreas bronchial epithelial cell pancreatic ductal cell apex of heartleft lobe of liver mesenteric lymph nodes right lung lobe left lung left lung lobe white adipose tissue spleen mucosa of small intestine subcutaneous adipose tissue embryo

Human Mouse (ortholog)

right lobe of liver right ventricle cardiac muscle tissue of right atrium right uterine tube myocardium of left ventricle right auricle of heart body of pancreas bronchial epithelial cell pancreatic ductal cell apex of heartleft lobe of liver mesenteric lymph nodes right lung lobe left lung left lung lobe white adipose tissue spleen mucosa of small intestine subcutaneous adipose tissue embryo

left lobe of liver mesenteric lymph nodes right lung lobe left lung left lung lobe white adipose tissue spleen mucosa of small intestine subcutaneous adipose tissue embryo

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtn/aRefSeq (mRNA)RefSeq (protein)n/aLocation (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt n/a

n/a

RefSeq (mRNA)

RefSeq (protein) n/a

n/a

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Complement component 6 is a protein that in humans is encoded by the C6 gene.

Complement component 6 is a protein involved in the complement system. It is part of the membrane attack complex which can insert into the cell membrane and cause the cell to lyse.

People with C6 deficiency are prone to bacterial infection.

External links

at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Complement component 6

Further reading

External links