Core binding factor
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The core binding factor (CBF) is a group of heterodimeric transcription factors.
Core binding factors are composed of:
- a non-DNA-binding CBFβ chain (InterPro: ) Human: CBFB
- a DNA-binding CBFα chain (InterPro: ) Human: RUNX1, RUNX2, RUNX3
- de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene. 23 (24): 4238–48. doi:. PMID .
See also
- AI-10-49, an anti-leukemic drug under development.
External links
- at the U.S. National Library of Medicine Medical Subject Headings (MeSH)