Cuyotenango is a town and municipality in the Suchitepéquez department of Guatemala. It has a population of 38,791.

Cuyotenango was founded around the 16th century, and its name in Nahuatl literally means "Fortification of the Coyote", a name given by the Mexican soldiers accompanying Pedro de Alvarado, the Spanish conquistador of Guatemala. There is a beach called Tulate, a vacation spot of Semana Santa (Holy Week).

14°32′N 91°34′W/14.533°N 91.567°W/ 14.533; -91.567