Deoxycytidine diphosphate is a nucleoside diphosphate. It is related to the common nucleic acid CTP, or cytidine triphosphate, with the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose removed (hence the deoxy- part of the name), and with one fewer phosphoryl group than CTP .

2'-Deoxycytidine diphosphate is abbreviated as dCDP.

Synthesis of cytidine nucleotides

Deoxycytidine diphosphate is synthesized through the oxidation-reduction reaction of cytidine 5'-diphosphocholine which is catalyzed by the presence of ribonucleoside-diphosphate reductase. Additionally, ribonucleoside-diphosphate reductase is capable of binding and catalyzing both the formation of deoxyribonucleotides from ribonucleotide.

See also

Further reading

  • Kennedy, Eugene P.; Louise Fencil Borkenhagen; Sylvia Wagner Smith (1959). . Journal of Biological Chemistry. 234 (8): 1998–2000. doi:. PMID .
  • Reichard, Peter (1962). . Journal of Biological Chemistry. 237: 3513–3519. doi:. PMID ..