DEFB103A

DEFB103B

Available structuresPDBHuman UniProt search:List of PDB id codes

Available structures

PDBHuman UniProt search:

List of PDB id codes

Identifiers

Aliases, BD-3, DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3, defensin beta 103B

External IDsOMIM: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 8 (human)

Band 8p23.1 Start 7,428,888 bp

End7,430,348 bp

RNA expression patternHumanMouse (ortholog)testicle cell tonsil monocyte blood cervix ectocervix mucosa of esophagus exocrine gland fundusn/an/a

RNA expression pattern

HumanMouse (ortholog)testicle cell tonsil monocyte blood cervix ectocervix mucosa of esophagus exocrine gland fundusn/a

Human Mouse (ortholog)

testicle cell tonsil monocyte blood cervix ectocervix mucosa of esophagus exocrine gland fundusn/a

testicle cell tonsil monocyte blood cervix ectocervix mucosa of esophagus exocrine gland fundus

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrezn/aEnsembln/aUniProtn/aRefSeq (mRNA)n/aRefSeq (protein)n/aLocation (UCSC)n/aPubMed searchn/a

Orthologs

Species Human Mouse

Entrez n/a

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Ensembl n/a

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UniProt n/a

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RefSeq (mRNA) n/a

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RefSeq (protein) n/a

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Location (UCSC) n/a

PubMed search n/a

Wikidata

View/Edit Human

Beta-defensin 103 is a protein that in humans is encoded by the DEFB103A gene.

Function

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.

In dogs, the product of the same genetic locus, β-Defensin 103, also plays a role in pigmentation, being an agonist of the melanocortin 1 receptor.

DEFB103A

Function

Further reading