Delta-like 1

DLL1

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Identifiers

Aliases, DELTA1, DL1, Delta, Delta-like 1, delta like canonical Notch ligand 1, NEDBAS

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 6 (human)

Band 6q27 Start 170,282,206 bp

End170,306,565 bp

Gene location ( Mouse )

Chr.Chromosome 17 (mouse)

Band 17 A2|17 8.95 cM Start 15,587,616 bp

End15,597,134 bp

RNA expression pattern

HumanMouse (ortholog)spleen ventricular zone skin of abdomen skin of leg prostate apex of heart mucosa of esophagus vagina right auricle of heart minor salivary glandsparaxial mesoderm tail of embryo ventricular zone primitive streak ciliary body tongue muscle corneal stroma ganglionic eminence medial ganglionic eminence right lung

Human Mouse (ortholog)

spleen ventricular zone skin of abdomen skin of leg prostate apex of heart mucosa of esophagus vagina right auricle of heart minor salivary glandsparaxial mesoderm tail of embryo ventricular zone primitive streak ciliary body tongue muscle corneal stroma ganglionic eminence medial ganglionic eminence right lung

spleen ventricular zone skin of abdomen skin of leg prostate apex of heart mucosa of esophagus vagina right auricle of heart minor salivary glands

paraxial mesoderm tail of embryo ventricular zone primitive streak ciliary body tongue muscle corneal stroma ganglionic eminence medial ganglionic eminence right lung

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene.

Function

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.

Interactions

Delta-like 1 has been shown to interact with NOTCH2.

Delta-like 1

Function

Interactions

Further reading