Desoxycorticosterone acetate

Clinical data

Trade namesPercorten Acetate, Decosterone, others

Other namesDOCA; 11-Deoxycorticosterone 21-acetate; 21-Acetoxypregn-4-ene-3,20-dione

Routes of administrationIntramuscular injection

Drug classCorticosteroid; Mineralocorticoid

Identifiers

IUPAC name [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

PubChem CID

CompTox Dashboard (EPA)

ECHA InfoCard

Chemical and physical data

FormulaC23H32O4

Molar mass372.505 g·mol−1

3D model (JSmol)

SMILES CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

InChI InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1Key:VPGRYOFKCNULNK-ACXQXYJUSA-N

Desoxycorticosterone acetate (also known as DOCA and 11-deoxycorticosterone 21-acetate and sold under the brand names Percorten Acetate and Decosterone, among others) is a mineralocorticoid medication and a mineralocorticoid ester. It is formulated as an oil solution and is administered once daily by intramuscular injection. The medication is the C21 acetate ester of 11-deoxycorticosterone.