Excitatory amino acid transporter 5

SLC1A7

Identifiers

Aliases, AAAT, EAAT5, solute carrier family 1 member 7

External IDsOMIM: ; MGI: ; GeneCards:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p32.3 Start 53,087,179 bp

End53,142,638 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 C7 Start 107,825,529 bp

End107,870,729 bp

RNA expression patternHumanMouse (ortholog)gastric mucosa granulocyte jejunal mucosa right ovary gallbladder tibial nerve left ovary testicle right coronary artery left uterine tubeneural layer of retina epithelium of lens outer nuclear layer retinal pigment epithelium inner nuclear layer left lobe of liver spermatid skin of abdomen pituitary gland testiclen/a

RNA expression pattern

HumanMouse (ortholog)gastric mucosa granulocyte jejunal mucosa right ovary gallbladder tibial nerve left ovary testicle right coronary artery left uterine tubeneural layer of retina epithelium of lens outer nuclear layer retinal pigment epithelium inner nuclear layer left lobe of liver spermatid skin of abdomen pituitary gland testicle

Human Mouse (ortholog)

gastric mucosa granulocyte jejunal mucosa right ovary gallbladder tibial nerve left ovary testicle right coronary artery left uterine tubeneural layer of retina epithelium of lens outer nuclear layer retinal pigment epithelium inner nuclear layer left lobe of liver spermatid skin of abdomen pituitary gland testicle

gastric mucosa granulocyte jejunal mucosa right ovary gallbladder tibial nerve left ovary testicle right coronary artery left uterine tube

neural layer of retina epithelium of lens outer nuclear layer retinal pigment epithelium inner nuclear layer left lobe of liver spermatid skin of abdomen pituitary gland testicle

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsDatabasesNCBI: ; OMA:SpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

DatabasesNCBI: ; OMA:

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Excitatory amino-acid transporter 5 (EAAT5) is a protein that in humans is encoded by the SLC1A7 gene.

EAAT5 is expressed predominantly in the retina, has high affinity for the excitatory amino acid L-glutamate. When stimulated by this amino acid, EAAT5 conducts chloride ions.

Excitatory amino acid transporter 5

Further reading