EIF2S3

Identifiers

Aliases, EIF2, EIF2G, EIF2gamma, eIF-2gA, eukaryotic translation initiation factor 2 subunit gamma, MRXSBRK, MEHMO

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.X chromosome (human)

Band Xp22.11 Start 24,054,946 bp

End24,078,810 bp

Gene location ( Mouse )

Chr.X chromosome (mouse)

Band X C3|X 41.52 cM Start 93,232,313 bp

End93,256,468 bp

RNA expression pattern

HumanMouse (ortholog)germinal epithelium parietal pleura skin of arm visceral pleura tibia mucosa of ileum monocyte epithelium of nasopharynx palpebral conjunctiva epithelium of colonmolar maxillary prominence genital tubercle mandibular prominence hand epiblast foot ventricular zone medial ganglionic eminence atrium

Human Mouse (ortholog)

germinal epithelium parietal pleura skin of arm visceral pleura tibia mucosa of ileum monocyte epithelium of nasopharynx palpebral conjunctiva epithelium of colonmolar maxillary prominence genital tubercle mandibular prominence hand epiblast foot ventricular zone medial ganglionic eminence atrium

germinal epithelium parietal pleura skin of arm visceral pleura tibia mucosa of ileum monocyte epithelium of nasopharynx palpebral conjunctiva epithelium of colon

molar maxillary prominence genital tubercle mandibular prominence hand epiblast foot ventricular zone medial ganglionic eminence atrium

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 2 subunit 3 (eIF2γ) is a protein that in humans is encoded by the EIF2S3 gene.

Function

Eukaryotic translation initiation factor 2 (eIF2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. eIF2 is composed of three subunits, alpha (α), beta (β), and gamma (γ, this article), with the protein encoded by this gene representing the gamma subunit.

EIF2S3

Function

See also

Further reading