FEZ2

Identifiers

Aliases, HUM3CL, fasciculation and elongation protein zeta 2

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 2 (human)

Band 2p22.2 Start 36,531,805 bp

End36,646,087 bp

Gene location ( Mouse )

Chr.Chromosome 17 (mouse)

Band 17 E2- E3|17 48.57 cM Start 78,676,641 bp

End78,725,581 bp

RNA expression pattern

HumanMouse (ortholog)endothelial cell secondary oocyte Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii thoracic diaphragm deltoid muscle parietal pleura muscle of thigh visceral pleura Brodmann area 23epithelium of lens sternocleidomastoid muscle muscle of thigh triceps brachii muscle retinal pigment epithelium right ventricle temporal muscle quadriceps femoris muscle digastric muscle gastrocnemius muscle

Human Mouse (ortholog)

endothelial cell secondary oocyte Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii thoracic diaphragm deltoid muscle parietal pleura muscle of thigh visceral pleura Brodmann area 23epithelium of lens sternocleidomastoid muscle muscle of thigh triceps brachii muscle retinal pigment epithelium right ventricle temporal muscle quadriceps femoris muscle digastric muscle gastrocnemius muscle

epithelium of lens sternocleidomastoid muscle muscle of thigh triceps brachii muscle retinal pigment epithelium right ventricle temporal muscle quadriceps femoris muscle digastric muscle gastrocnemius muscle

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene.

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.

Interactions

FEZ2 has been shown to interact with Protein kinase Mζ.

FEZ2

Interactions

Further reading