FRMPD4

Available structuresPDBOrtholog search:List of PDB id codes, , ,

Available structures

PDBOrtholog search:

List of PDB id codes, , ,

List of PDB id codes

, , ,

Identifiers

Aliases, PDZD10, PDZK10, FERM and PDZ domain containing 4, MRX104

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.X chromosome (human)

Band Xp22.2 Start 12,138,466 bp

End12,724,523 bp

Gene location ( Mouse )

Chr.X chromosome (mouse)

Band X|X F5 Start 166,254,305 bp

End167,360,227 bp

RNA expression patternHumanMouse (ortholog)middle temporal gyrus endothelial cell Brodmann area 23 Brodmann area 46 orbitofrontal cortex superior frontal gyrus postcentral gyrus primary visual cortex entorhinal cortex prefrontal cortexdentate gyrus of hippocampal formation granule cell hippocampus proper primary visual cortex superior frontal gyrus cerebellum cerebellar cortex striatum of neuraxis vasculature vasculature of organ olfactory bulbn/a

RNA expression pattern

HumanMouse (ortholog)middle temporal gyrus endothelial cell Brodmann area 23 Brodmann area 46 orbitofrontal cortex superior frontal gyrus postcentral gyrus primary visual cortex entorhinal cortex prefrontal cortexdentate gyrus of hippocampal formation granule cell hippocampus proper primary visual cortex superior frontal gyrus cerebellum cerebellar cortex striatum of neuraxis vasculature vasculature of organ olfactory bulb

Human Mouse (ortholog)

middle temporal gyrus endothelial cell Brodmann area 23 Brodmann area 46 orbitofrontal cortex superior frontal gyrus postcentral gyrus primary visual cortex entorhinal cortex prefrontal cortexdentate gyrus of hippocampal formation granule cell hippocampus proper primary visual cortex superior frontal gyrus cerebellum cerebellar cortex striatum of neuraxis vasculature vasculature of organ olfactory bulb

middle temporal gyrus endothelial cell Brodmann area 23 Brodmann area 46 orbitofrontal cortex superior frontal gyrus postcentral gyrus primary visual cortex entorhinal cortex prefrontal cortex

dentate gyrus of hippocampal formation granule cell hippocampus proper primary visual cortex superior frontal gyrus cerebellum cerebellar cortex striatum of neuraxis vasculature vasculature of organ olfactory bulb

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

FERM and PDZ domain containing 4 is a protein that in humans is encoded by the FRMPD4 gene.

Function

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission.

FRMPD4

Function

Further reading