FXR2

Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene.

Function

The protein encoded by this gene is an RNA-binding protein containing two KH domains and one RCG box, similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may play a role in the development of fragile X intellectual disability syndrome.

Interactions

FXR2 has been shown to interact with:

• CYFIP2,
• FMR1,
• FXR1, and
• LCMT1.

Further reading