Frizzled-1 (Fz-1) is a protein that in humans is encoded by the FZD1 gene.

Function

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

Further reading

External links

  • . IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from on 2016-03-03.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.