Gem-associated protein 5

GEMIN5

Identifiers

Aliases, GEMIN-5, gem nuclear organelle associated protein 5, NEDCAM

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 5 (human)

Band 5q33.2 Start 154,887,411 bp

End154,938,211 bp

Gene location ( Mouse )

Chr.Chromosome 11 (mouse)

Band 11|11 B1.3 Start 58,010,828 bp

End58,059,365 bp

RNA expression pattern

HumanMouse (ortholog)oocyte secondary oocyte tibialis anterior muscle gonad deltoid muscle ventricular zone biceps brachii Skeletal muscle tissue of biceps brachii gastrocnemius muscle quadriceps femoris musclespermatocyte spermatid epiblast tail of embryo seminiferous tubule internal carotid artery morula morula genital tubercle intestinal villus

Human Mouse (ortholog)

oocyte secondary oocyte tibialis anterior muscle gonad deltoid muscle ventricular zone biceps brachii Skeletal muscle tissue of biceps brachii gastrocnemius muscle quadriceps femoris musclespermatocyte spermatid epiblast tail of embryo seminiferous tubule internal carotid artery morula morula genital tubercle intestinal villus

oocyte secondary oocyte tibialis anterior muscle gonad deltoid muscle ventricular zone biceps brachii Skeletal muscle tissue of biceps brachii gastrocnemius muscle quadriceps femoris muscle

spermatocyte spermatid epiblast tail of embryo seminiferous tubule internal carotid artery morula morula genital tubercle intestinal villus

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Gem-associated protein 5 is a protein that in humans is encoded by the GEMIN5 gene.

Function

Gem-associated protein 5 is part of the SMN a large protein complex localized to both the cytoplasm and the nucleus that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), gem-associated protein 2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), and GEMIN4 (MIM 606969).

Interactions

GEMIN5 has been shown to interact with DDX20 and SMN1.

Gem-associated protein 5

Function

Interactions

Further reading