GemOx
In-game article clicks load inline without leaving the challenge.
GemOx or GEMOX is an acronym for one of the chemotherapy regimens used in the treatment of relapsed or primary refractory non-Hodgkin lymphoma and Hodgkin lymphoma.
When combined with Rituximab it is called R-GemOx, R-GEMOX or GemOx-R, GEMOX-R.
The [R]-GemOx regimen consists of:
- Rituximab - anti-CD20 monoclonal antibody that has the ability to kill both normal and malignant B cells;
- Gemcitabine - an antimetabolite;
- Oxaliplatin - a platinum-based alkylating antineoplastic agent.
Dosing regimen
| Drug | Dose | Mode | Days |
|---|---|---|---|
| Rituximab | 375 mg/m2 | IV infusion | Day 1 |
| Gemcitabine | 1000 mg/m2 | IV infusion in 500 ml normal saline with the speed of 10 mg/m2/min | Day 2 |
| Oxaliplatin | 100 mg/m2 | IV infusion over 2hrs | Day 2 |