GRIK5

Identifiers

Aliases, EAA2, GRIK2, GluK5, KA2, glutamate ionotropic receptor kainate type subunit 5

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 19 (human)

Band 19q13.2 Start 41,998,321 bp

End42,070,206 bp

Gene location ( Mouse )

Chr.Chromosome 7 (mouse)

Band 7 A3|7 13.73 cM Start 25,009,849 bp

End25,072,346 bp

RNA expression pattern

HumanMouse (ortholog)olfactory bulb lateral nuclear group of thalamus ventral tegmental area subthalamic nucleus vena cava superior vestibular nucleus inferior ganglion of vagus nerve pons external globus pallidus pars compactasuperior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell entorhinal cortex perirhinal cortex CA3 field neural layer of retina olfactory tubercle ventricular zone primary motor cortex

Human Mouse (ortholog)

olfactory bulb lateral nuclear group of thalamus ventral tegmental area subthalamic nucleus vena cava superior vestibular nucleus inferior ganglion of vagus nerve pons external globus pallidus pars compactasuperior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell entorhinal cortex perirhinal cortex CA3 field neural layer of retina olfactory tubercle ventricular zone primary motor cortex

superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell entorhinal cortex perirhinal cortex CA3 field neural layer of retina olfactory tubercle ventricular zone primary motor cortex

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Glutamate receptor, ionotropic kainate 5 is a protein that in humans is encoded by the GRIK5 gene.

Function

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.

Interactions

GRIK5 has been shown to interact with DLG4 and GRIK2.

External links

at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

GRIK5

Function

Interactions

See also

Further reading

External links