H1FOO

H1-8

Identifiers

Aliases, osH1, H1.8, H1oo, H1 histone family member O, oocyte specific, H1 histone family member O oocyte specific, H1.8 linker histone, H1FOO

External IDsMGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 3 (human)

Band 3q22.1 Start 129,543,175 bp

End129,551,467 bp

Gene location ( Mouse )

Chr.Chromosome 6 (mouse)

Band 6|6 E3 Start 115,921,899 bp

End115,927,197 bp

RNA expression patternHumanMouse (ortholog)oocyte secondary oocyte left testis right testis gonad mucosa of nose human musculoskeletal system anterior pituitary olfactory zone of nasal mucosa muscular systemzygote secondary oocyte primary oocyte cardiac muscle tissue of left ventricle extensor digitorum longus muscle interventricular septum plantaris muscle embryo cingulate gyrus morulan/a

RNA expression pattern

HumanMouse (ortholog)oocyte secondary oocyte left testis right testis gonad mucosa of nose human musculoskeletal system anterior pituitary olfactory zone of nasal mucosa muscular systemzygote secondary oocyte primary oocyte cardiac muscle tissue of left ventricle extensor digitorum longus muscle interventricular septum plantaris muscle embryo cingulate gyrus morula

Human Mouse (ortholog)

oocyte secondary oocyte left testis right testis gonad mucosa of nose human musculoskeletal system anterior pituitary olfactory zone of nasal mucosa muscular systemzygote secondary oocyte primary oocyte cardiac muscle tissue of left ventricle extensor digitorum longus muscle interventricular septum plantaris muscle embryo cingulate gyrus morula

oocyte secondary oocyte left testis right testis gonad mucosa of nose human musculoskeletal system anterior pituitary olfactory zone of nasal mucosa muscular system

zygote secondary oocyte primary oocyte cardiac muscle tissue of left ventricle extensor digitorum longus muscle interventricular septum plantaris muscle embryo cingulate gyrus morula

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Histone H1oo is a protein that in humans is encoded by the H1FOO gene.

Function

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.

It incorporates into sperm chromatin after fertilisation.

H1FOO

Function

Further reading