HOXB3

Identifiers

Aliases, HOX2, HOX2G, Hox-2.7, homeobox B3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 17 (human)

Band 17q21.32 Start 48,548,870 bp

End48,604,912 bp

Gene location ( Mouse )

Chr.Chromosome 11 (mouse)

Band 11 D|11 59.84 cM Start 96,214,152 bp

End96,238,756 bp

RNA expression pattern

HumanMouse (ortholog)right uterine tube corpus epididymis caput epididymis seminal vesicula gastric mucosa muscle layer of sigmoid colon tail of epididymis transverse colon beta cell endometriumefferent ductule migratory enteric neural crest cell tail of embryo vas deferens medullary collecting duct inferior ganglion of vagus nerve hair follicle abdominal wall Paneth cell thoracic vertebral column

Human Mouse (ortholog)

right uterine tube corpus epididymis caput epididymis seminal vesicula gastric mucosa muscle layer of sigmoid colon tail of epididymis transverse colon beta cell endometriumefferent ductule migratory enteric neural crest cell tail of embryo vas deferens medullary collecting duct inferior ganglion of vagus nerve hair follicle abdominal wall Paneth cell thoracic vertebral column

right uterine tube corpus epididymis caput epididymis seminal vesicula gastric mucosa muscle layer of sigmoid colon tail of epididymis transverse colon beta cell endometrium

efferent ductule migratory enteric neural crest cell tail of embryo vas deferens medullary collecting duct inferior ganglion of vagus nerve hair follicle abdominal wall Paneth cell thoracic vertebral column

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).

External links

at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

HOXB3

See also

Further reading

External links