Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

The protein encoded by this gene is a member of kinesin-like protein family, and contains common ATPase site structures such as the P-loop, Switch 1, and Switch 2. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.

A ribbon and surface diagram of the KIF2C motor domain. The kinesin structure is pseudo-colored to highlight the ATPase site with a bound nucleotide. The figure then presents KIF2C binding to the tubulin dimer and finally visualizes a KIF2C motor head in the context of the microtubule filament.

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: (Kinesin-like protein KIF2C) at the PDBe-KB.