Keratin 2A

KRT2

Identifiers

Aliases, CK-2e, K2e, KRT2A, KRT2E, KRTE, keratin 2

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 12 (human)

Band 12q13.13 Start 52,644,558 bp

End52,652,211 bp

Gene location ( Mouse )

Chr.Chromosome 15 (mouse)

Band 15 F2|15 57.03 cM Start 101,719,124 bp

End101,726,604 bp

RNA expression patternHumanMouse (ortholog)skin of arm skin of thigh skin of hip skin of abdomen nipple human penis gingival epithelium vulva palpebral conjunctiva gastrocnemius muscleskin of external ear lip dentate gyrus of hippocampal formation granule cell ankle ankle joint Ileal epithelium entorhinal cortex filiform papilla stellate ganglion ganglion of vagus nerven/a

RNA expression pattern

HumanMouse (ortholog)skin of arm skin of thigh skin of hip skin of abdomen nipple human penis gingival epithelium vulva palpebral conjunctiva gastrocnemius muscleskin of external ear lip dentate gyrus of hippocampal formation granule cell ankle ankle joint Ileal epithelium entorhinal cortex filiform papilla stellate ganglion ganglion of vagus nerve

Human Mouse (ortholog)

skin of arm skin of thigh skin of hip skin of abdomen nipple human penis gingival epithelium vulva palpebral conjunctiva gastrocnemius muscleskin of external ear lip dentate gyrus of hippocampal formation granule cell ankle ankle joint Ileal epithelium entorhinal cortex filiform papilla stellate ganglion ganglion of vagus nerve

skin of arm skin of thigh skin of hip skin of abdomen nipple human penis gingival epithelium vulva palpebral conjunctiva gastrocnemius muscle

skin of external ear lip dentate gyrus of hippocampal formation granule cell ankle ankle joint Ileal epithelium entorhinal cortex filiform papilla stellate ganglion ganglion of vagus nerve

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Keratin 2A also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene.

Keratin 2A is a type II cytokeratin. It is found largely in the upper spinous layer of epidermal keratinocytes and mutations in the gene encoding this protein have been associated with ichthyosis bullosa of Siemens.

External links

at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Keratin 2A

Further reading

External links