Kinamycin
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Kinamycins are a group of bacterial polyketide secondary metabolites containing a diazo group. Kinamycins are known for their cytotoxicity and are considered of interest for potential use in anti-cancer therapies.
Synthesis
In 2006 and 2007 the means to totally and enantioselectively synthesize kinamycins C, F, and J were discovered. In 2010 a method was found to allow easier synthesis of these compounds in fewer steps, making research into their properties more feasible.
External links
- EMBL-EBI listing—includes links to structural formula and other properties of group members