U6 snRNA-associated Sm-like protein LSm2 is a protein that in humans is encoded by the LSM2 gene.

Function

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM]

Interactions

LSM2 has been shown to interact with DDX20, LSM3, LSM8 and LSM7.

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: (U6 snRNA-associated Sm-like protein LSm2) at the PDBe-KB.