Large subunit ribosomal ribonucleic acid (LSU rRNA) is the largest of the two major RNA components of the ribosome. Associated with a number of ribosomal proteins, the LSU rRNA forms the large subunit of the ribosome. The LSU rRNA acts as a ribozyme, catalyzing peptide bond formation.

Characteristics

Characteristics of the LSU rRNA for exemplary species.
TypeLSU rRNA sizeSpeciesLengthAccessionReference
Bacterial (Prokaryotic)23SEscherichia coli2,905 ntNR_076322.1
Archaeal (Prokaryotic)23SHalobacterium salinarum2,906 ntNR_076247.1
Eukaryotic5.8S & 28SHomo sapiens157 + 5,025 ntNR_145821.1; M11167.1
Mitochondrial16SHomo sapiens1,559 ntNC_012920.1
Plastid23SArabidopsis thaliana2,810 ntNC_000932.1

Use in phylogenetics

LSU rRNA sequences are widely used for working out evolutionary relationships among organisms, since they are of ancient origin and are found in all known forms of life.

See also

  • SSU rRNA: the small subunit ribosomal ribonucleic acid.