The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins.

LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of transforming growth factors. They interact with a variety of extracellular matrix proteins and may play a role in the regulation of TGF beta bioavailability.

Genes

latent transforming growth factor beta binding protein 1
latent transforming growth factor beta binding protein 1IdentifiersSymbolLTBP1Alt. symbolsTGF-beta1-BP-1NCBI geneHGNCOMIMRefSeqUniProtOther dataLocusChr. 2Search forStructuresDomainslatent transforming growth factor beta binding protein 2IdentifiersSymbolLTBP2Alt. symbolsLTBP3, C14orf141NCBI geneHGNCOMIMRefSeqUniProtOther dataLocusChr. 14Search forStructuresDomainslatent transforming growth factor beta binding protein 3IdentifiersSymbolLTBP3Alt. symbolsLTBP2NCBI geneHGNCOMIMRefSeqUniProtOther dataLocusChr. 11Search forStructuresDomainslatent transforming growth factor beta binding protein 4IdentifiersSymbolLTBP4Alt. symbolsLTBP-4, LTBP-4LNCBI geneHGNCOMIMRefSeqUniProtOther dataLocusChr. 19Search forStructuresDomains
Identifiers
SymbolLTBP1
Alt. symbolsTGF-beta1-BP-1
NCBI gene
HGNC
OMIM
RefSeq
UniProt
Other data
LocusChr. 2
Search forStructuresDomains
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Structures
Domains
latent transforming growth factor beta binding protein 2
Identifiers
SymbolLTBP2
Alt. symbolsLTBP3, C14orf141
NCBI gene
HGNC
OMIM
RefSeq
UniProt
Other data
LocusChr. 14
Search forStructuresDomains
Search for
Structures
Domains
latent transforming growth factor beta binding protein 3
Identifiers
SymbolLTBP3
Alt. symbolsLTBP2
NCBI gene
HGNC
OMIM
RefSeq
UniProt
Other data
LocusChr. 11
Search forStructuresDomains
Search for
Structures
Domains
latent transforming growth factor beta binding protein 4
Identifiers
SymbolLTBP4
Alt. symbolsLTBP-4, LTBP-4L
NCBI gene
HGNC
OMIM
RefSeq
UniProt
Other data
LocusChr. 19
Search forStructuresDomains
Search for
Structures
Domains

External links

  • at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  • provides an overview of all the structure information available in the PDB for Human Latent-transforming growth factor beta-binding protein 1