A list of more than 100 different single cell sequencing (omics) methods have been published. The large majority of methods are paired with short-read sequencing technologies, although some of them are compatible with long read sequencing.

List

MethodReferenceSequencing ModeEarly EstimateLate Estimate
Tang methodShort Reads20082009
CyTOFShort Reads20112012
STRT-seq / C1Short Reads20112012
SMART-seqShort Reads20122013
CEL-seqShort Reads20122013
Quartz-SeqShort Reads20122013
PMA / SMAShort Reads20122013
scBS-seqShort Reads20132014
AbPairShort Reads20142014
MARS-seqShort Reads20142015
DR-seqShort Reads20142015
G&T-seqShort Reads20142015
SCTGShort Reads20142015
SIDR-seqShort Reads20142015
sci-ATAC-seqShort Reads20142015
Hi-SCLShort Reads20152015
SUPeR-seqShort Reads20152015
Drop-ChipShort Reads20152015
CytoSeqShort Reads20152016
inDropShort Reads20152016
sc-GEMShort Reads20152016
scTrio-seqShort Reads20152016
scM&T-seqShort Reads20152016
PLAYRShort Reads20152016
Genshaft-et-al-2016Short Reads20152016
Darmanis-et-al-2016Short Reads20152016
CRISP-seqShort Reads20152016
scGESTALTShort Reads20152016
CEL-Seq2 / C1Short Reads20152016
STRT-seq-2iShort Reads20162017
RNAseq @10xgenomicsShort Reads20162017
RNAseq / Gene Expression @nanostringtechShort Reads20162017
sc Targeted Gene Expression @fluidigmShort Reads20162017
scTCR WafergenShort Reads20162017
CROP-seqShort Reads20162017
SiC-seqShort Reads20162017
mcSCRB-seqShort Reads20162017
Patch-seqShort Reads20162017
Geo-seqShort Reads20162017
scNOMe-seqShort Reads20162017
scCOOL-seqShort Reads20162017
CUT&RunShort Reads20162017
MATQ-seqShort Reads20162017
Quartz-Seq2Short Reads20172018
Seq-WellShort Reads20172018
DroNC-SeqShort Reads20172018
sci-RNA-seqShort Reads20172018
scATAC @10xgenomicsShort Reads20172018
scVDJ @10xgenomicsShort Reads20172018
scNMT triple omicsShort Reads20172018
SPLIT-seq Parse BiosciencesShort Reads20172018
CITE-SeqShort Reads20172018
scMNase-seqShort Reads20172018
Chaligne-et-al-2018Short Reads20172018
LINNAEUSShort Reads20172018
TracerSeqShort Reads20172018
CellTagShort Reads20172018
ScarTraceShort Reads20172018
scRNA-Seq Dolomite BioShort Reads20172018
Trac-loopingShort Reads20172018
Perturb-ATACShort Reads20182019
scMethylationShort Reads20182019
scHiCShort Reads20182019
Multiplex Droplet scRNAseqShort Reads20182019
sci-CARShort Reads20182019
C1 CAGE single cellShort Reads20182019
sc paired microRNA-mRNAShort Reads20182019
scCAT-seqShort Reads20182019
REAP-seq @fluidigmShort Reads20182019
scCCShort Reads20182019
yscRNA-SEQShort Reads20182019
TARGET-seqShort Reads20182019
MULTI-seqShort Reads20182019
snRNA-seqShort Reads20182019
sci-RNA-seq3Short Reads20182019
BRIF-seqShort Reads20182019
Drop-seq Dolomite BioShort Reads20182019
Slide-seqShort Reads20182019
CUT&TagShort Reads20182019
CellTaggingShort Reads20182019
DART-SeqShort Reads20182019
scDamID&TShort Reads20182019
ACT-seqShort Reads20182019
Sci-Hi-CShort Reads20182019
Slide-seqShort Reads20182019
Simplified-Drop-seqShort Reads20182019
scChIC-seqShort Reads20182019
Dip-CShort Reads20182019
CoBATCHShort Reads20182019
Convert-seqShort Reads20182019
Droplet-based scATAC-seqShort Reads20182019
ECCITE-seqShort Reads20182019
dsciATAC-seqShort Reads20182019
CLEVER-seqShort Reads20182019
scISOr-SeqShort Reads20182019
MARS-seq2.0Short Reads20182019
nano-NOMeLong Reads20182019
MeSMLR-seqLong Reads20182019
SMAC-seqLong Reads20182019
MoonTag/SunTagShort Reads20182019
SCoPE2Short Reads20182019
sci-fateShort Reads20182019
μDamIDShort Reads20182019
Methyl-HiCShort Reads20182019
RAGE-seqLong Reads20182019
Paired-SeqShort Reads20182019
Tn5PrimeShort Reads20182019
NanoPAREShort Reads20182019
BART-SeqShort Reads20182019
scDam&T-seqShort Reads20182019
itChIP-seqShort Reads20182019
SNARE-seqShort Reads20182019
ASTAR-seqShort Reads20182019
sci-PlexShort Reads20182019
MIX-SeqShort Reads20182019
microSPLiTShort Reads20182019
PAIso-seqShort Reads20182019
FIN-SeqShort Reads20182019
LIBRA-seqShort Reads20182019
scifi-RNA-seqShort Reads20182019
plexDIAShort Reads20212021
scGET-seqShort Reads20222022
MPXShort Reads20232023