The Little Four Conference was a short-lived IHSAA-sanctioned conference in Central Indiana. The conference began in 1971, as the remaining three Big Four Conference schools joined with local team Eminence, who had been independent since the demise of the Little Eight Conference in 1964. The conference folded when Granville Wells consolidated into Western Boone. Within two years, Eminence would be the only school left from the four teams.

SchoolLocationMascotColorsCountyYear joinedPrevious conferenceYear leftConference joined
EminenceEminenceEels55 Morgan1971Independents (L8C 1964)1974Independents (TRC 1986)
Granville Wells1JamestownRockets06 Boone1971Big 41974none (consolidated into Western Boone
North SalemNorth SalemBlue Devils32 Hendricks1971Big 41974Independents (closed 1976)
PittsboroPittsboroBurros32 Hendricks1971Big 41974Independents (closed 1976)