MAD2L2

Available structuresPDBOrtholog search:List of PDB id codes, , , , ,

Available structures

PDBOrtholog search:

List of PDB id codes, , , , ,

List of PDB id codes

, , , , ,

Identifiers

Aliases, MAD2B, POLZ2, REV7, MAD2 mitotic arrest deficient-like 2 (yeast), mitotic arrest deficient 2 like 2, FANCV

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p36.22 Start 11,674,480 bp

End11,691,650 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 E2 Start 148,130,384 bp

End148,145,699 bp

RNA expression patternHumanMouse (ortholog)ganglionic eminence left testis right testis granulocyte gastrocnemius muscle stromal cell of endometrium ventricular zone muscle of thigh right lobe of liver body of pancreasgenital tubercle seminiferous tubule tail of embryo spermatocyte zygote ventricular zone morula secondary oocyte external carotid artery neural tuben/a

RNA expression pattern

HumanMouse (ortholog)ganglionic eminence left testis right testis granulocyte gastrocnemius muscle stromal cell of endometrium ventricular zone muscle of thigh right lobe of liver body of pancreasgenital tubercle seminiferous tubule tail of embryo spermatocyte zygote ventricular zone morula secondary oocyte external carotid artery neural tube

Human Mouse (ortholog)

ganglionic eminence left testis right testis granulocyte gastrocnemius muscle stromal cell of endometrium ventricular zone muscle of thigh right lobe of liver body of pancreasgenital tubercle seminiferous tubule tail of embryo spermatocyte zygote ventricular zone morula secondary oocyte external carotid artery neural tube

ganglionic eminence left testis right testis granulocyte gastrocnemius muscle stromal cell of endometrium ventricular zone muscle of thigh right lobe of liver body of pancreas

genital tubercle seminiferous tubule tail of embryo spermatocyte zygote ventricular zone morula secondary oocyte external carotid artery neural tube

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

Function

MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.

Interactions

MAD2L2 has been shown to interact with:

MAD2L2

Function

Interactions

Further reading