MEE, also known as 2-methoxy-4,5-diethoxyamphetamine or as TMA2-4,5-DiEtO, is a chemical compound of the phenethylamine, amphetamine, and DOx families related to the psychedelic drug TMA-2. It is the analogue of TMA-2 in which the methoxy groups at the 4 and 5 positions have been replaced with ethoxy groups. In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MEE's dose as greater than 4.6mg orally and its duration as unknown. The drug produced no effects at tested doses. The chemical synthesis of MEE has been described. MEE was first described in the scientific literature by Shulgin in 1968. Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.

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