MMEL1

Identifiers

Aliases, MMEL2, NEP2, NEPII, NL1, NL2, SEP, membrane metallo-endopeptidase-like 1, membrane metalloendopeptidase like 1

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p36.32 Start 2,590,639 bp

End2,633,016 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 E2 Start 154,954,042 bp

End154,979,985 bp

RNA expression patternHumanMouse (ortholog)testicle gonad left testis right testis mucosa of transverse colon right uterine tube body of stomach duodenum right lung fundusspermatid seminiferous tubule spermatocyte embryo embryo neural layer of retina blastocyst facial motor nucleus epiblast cerebellar cortexn/a

RNA expression pattern

HumanMouse (ortholog)testicle gonad left testis right testis mucosa of transverse colon right uterine tube body of stomach duodenum right lung fundusspermatid seminiferous tubule spermatocyte embryo embryo neural layer of retina blastocyst facial motor nucleus epiblast cerebellar cortex

Human Mouse (ortholog)

testicle gonad left testis right testis mucosa of transverse colon right uterine tube body of stomach duodenum right lung fundusspermatid seminiferous tubule spermatocyte embryo embryo neural layer of retina blastocyst facial motor nucleus epiblast cerebellar cortex

testicle gonad left testis right testis mucosa of transverse colon right uterine tube body of stomach duodenum right lung fundus

spermatid seminiferous tubule spermatocyte embryo embryo neural layer of retina blastocyst facial motor nucleus epiblast cerebellar cortex

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Membrane metallo-endopeptidase-like 1 is a protein that in humans is encoded by the MMEL1 gene.

Function

The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.

MMEL1

Function

Further reading