Mlele District is one of the five districts of the Katavi Region of Tanzania.

Mlele District was formed in 2012 out of part of Mpanda District. The population in 2022 was 118,818.

Administrative subdivisions

Mlele District is administratively divided into twenty-three wards:

  • Ikuba
  • Ilela
  • Inyonga
  • Itenka
  • Kapalala
  • Kasansa
  • Kasokola
  • Kibaoni
  • Litapunga
  • Machimboni
  • Magamba
  • Majimoto
  • Mamba
  • Mbede
  • Mtapenda
  • Mwamapuli
  • Nsekwa
  • Nsimbo
  • Sitalike
  • Ugalla
  • Urwira
  • Usevya
  • Utende

6°35′24″S 31°45′54″E/6.590°S 31.765°E/ -6.590; 31.765