Mohammad-Reza Mirtajadini (Persian: محمدرضا میرتاج‌الدینی; born 16 March 1963) is an Iranian cleric and principlist politician. He was vice president for parliamentary affairs from 2009 to 2013 and a member of the parliament in two terms, from 2004 to 2009 and from 2020 to 2024. He was also an adviser of President Mahmoud Ahmadinejad in clerics subjects.