NKRF (gene)

NKRF

Identifiers

Aliases, ITBA4, NRF, NFKB repressing factor

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.X chromosome (human)

Band Xq24 Start 119,588,337 bp

End119,606,443 bp

Gene location ( Mouse )

Chr.X chromosome (mouse)

Band X|X A3.3 Start 36,151,193 bp

End36,167,166 bp

RNA expression pattern

HumanMouse (ortholog)postcentral gyrus Brodmann area 23 superior frontal gyrus middle temporal gyrus gonad entorhinal cortex primary visual cortex Brodmann area 46 pons prefrontal cortexpontine nuclei medial vestibular nucleus dorsal tegmental nucleus ventral tegmental area lateral hypothalamus primitive streak facial motor nucleus deep cerebellar nuclei spinal cord superior colliculus

Human Mouse (ortholog)

postcentral gyrus Brodmann area 23 superior frontal gyrus middle temporal gyrus gonad entorhinal cortex primary visual cortex Brodmann area 46 pons prefrontal cortexpontine nuclei medial vestibular nucleus dorsal tegmental nucleus ventral tegmental area lateral hypothalamus primitive streak facial motor nucleus deep cerebellar nuclei spinal cord superior colliculus

postcentral gyrus Brodmann area 23 superior frontal gyrus middle temporal gyrus gonad entorhinal cortex primary visual cortex Brodmann area 46 pons prefrontal cortex

pontine nuclei medial vestibular nucleus dorsal tegmental nucleus ventral tegmental area lateral hypothalamus primitive streak facial motor nucleus deep cerebellar nuclei spinal cord superior colliculus

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene.

This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes.

The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.

NKRF (gene)

Further reading