NRCAM

Available structuresPDBOrtholog search:List of PDB id codes,

Available structures

PDBOrtholog search:

List of PDB id codes,

List of PDB id codes

Identifiers

Aliases, neuronal cell adhesion molecule

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 7 (human)

Band 7q31.1 Start 108,147,623 bp

End108,456,717 bp

Gene location ( Mouse )

Chr.Chromosome 12 (mouse)

Band 12 B2|12 20.71 cM Start 44,328,885 bp

End44,601,964 bp

RNA expression pattern

HumanMouse (ortholog)lateral nuclear group of thalamus Brodmann area 23 middle temporal gyrus primary visual cortex Brodmann area 9 prefrontal cortex superior frontal gyrus entorhinal cortex right frontal lobe amygdalaepithelium of lens dentate gyrus of hippocampal formation granule cell subiculum primary visual cortex medial dorsal nucleus superior frontal gyrus prefrontal cortex anterior amygdaloid area median eminence arcuate nucleus

Human Mouse (ortholog)

lateral nuclear group of thalamus Brodmann area 23 middle temporal gyrus primary visual cortex Brodmann area 9 prefrontal cortex superior frontal gyrus entorhinal cortex right frontal lobe amygdalaepithelium of lens dentate gyrus of hippocampal formation granule cell subiculum primary visual cortex medial dorsal nucleus superior frontal gyrus prefrontal cortex anterior amygdaloid area median eminence arcuate nucleus

lateral nuclear group of thalamus Brodmann area 23 middle temporal gyrus primary visual cortex Brodmann area 9 prefrontal cortex superior frontal gyrus entorhinal cortex right frontal lobe amygdala

epithelium of lens dentate gyrus of hippocampal formation granule cell subiculum primary visual cortex medial dorsal nucleus superior frontal gyrus prefrontal cortex anterior amygdaloid area median eminence arcuate nucleus

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Neuronal cell adhesion molecule is a protein that in humans is encoded by the NRCAM gene.

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

NRCAM

Further reading