NXT1

Available structuresPDBOrtholog search:List of PDB id codes, ,

Available structures

PDBOrtholog search:

List of PDB id codes, ,

List of PDB id codes

, ,

Identifiers

Aliases, MTR2, P15, nuclear transport factor 2 like export factor 1

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 20 (human)

Band 20p11.21 Start 23,350,791 bp

End23,354,771 bp

Gene location ( Mouse )

Chr.Chromosome 2 (mouse)

Band 2|2 G3 Start 148,514,521 bp

End148,517,947 bp

RNA expression pattern

HumanMouse (ortholog)left uterine tube popliteal artery tibial arteries mucosa of urinary bladder olfactory zone of nasal mucosa ascending aorta left ovary granulocyte cartilage tissue skin of abdomenspermatocyte seminiferous tubule spermatid embryo embryo medullary collecting duct epiblast renal corpuscle maxillary prominence primary oocyte

Human Mouse (ortholog)

left uterine tube popliteal artery tibial arteries mucosa of urinary bladder olfactory zone of nasal mucosa ascending aorta left ovary granulocyte cartilage tissue skin of abdomenspermatocyte seminiferous tubule spermatid embryo embryo medullary collecting duct epiblast renal corpuscle maxillary prominence primary oocyte

left uterine tube popliteal artery tibial arteries mucosa of urinary bladder olfactory zone of nasal mucosa ascending aorta left ovary granulocyte cartilage tissue skin of abdomen

spermatocyte seminiferous tubule spermatid embryo embryo medullary collecting duct epiblast renal corpuscle maxillary prominence primary oocyte

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene.

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.

NXT1

Further reading